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Hypoosmolar hyponatremia is a condition where hyponatremia is associated with a low plasma osmolality. [1] The term "hypotonic hyponatremia" is also sometimes used.[2]When the plasma osmolarity is low, the extracellular fluid volume status may be in one of three states: low volume, normal volume, or high volume.
Hyponatremia or hyponatraemia is a low concentration of sodium in the blood. [4] It is generally defined as a sodium concentration of less than 135 mmol/L (135 mEq/L), with severe hyponatremia being below 120 mEq/L. [3] [8] Symptoms can be absent, mild or severe.
There are nine supplemental features: 1) a low BUN; 2) a low uric acid; 3) a normal creatinine; 4) failure to correct hyponatremia with IV normal saline; 5) successful correction of hyponatremia with fluid restriction; 6) a fractional sodium excretion >1%; 7) a fractional urea excretion >55%; 8) an abnormal water load test; and 9) an elevated ...
Although hyponatremia is a fairly common condition, many patients have only mildly decreased blood sodium. Skip to main content. 24/7 Help. For premium support please call: 800-290-4726 more ...
It is generally defined as a concentration lower than 135 mEq/L. [3] This relatively common electrolyte disorder can indicate the presence of a disease process, but in the hospital setting is more often due to administration of Hypotonic fluids. [14] [3] The majority of hospitalized patients only experience mild hyponatremia, with levels above ...
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An iso-osmolar solution can be hypotonic if the solute is able to penetrate the cell membrane. For example, an iso-osmolar urea solution is hypotonic to red blood cells, causing their lysis . This is due to urea entering the cell down its concentration gradient, followed by water.