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Chemical structure of modafinil. This page lists chemical compounds similar to modafinil, known as modafinil analogues and derivatives. These are structural analogues and derivatives of modafinil, a drug that affects dopamine levels in the brain in an unusual way (atypical dopamine reuptake inhibitor or DRI).
In a 2006 study, a single dose of modafinil 200 mg caused a decrease in blood prolactin levels, although it did not affect human growth hormone or thyroid-stimulating hormone. [88] [144] Since modafinil induces the activity of the CYP3A4 enzyme involved in cortisol clearance, [145] modafinil may reduce the bioavailability of hydrocortisone ...
At steady state, the systemic exposure for armodafinil is 1.8 times the exposure observed after a single dose. The concentration-time profiles of the (R)-(−)-enantiomer following a single dose of 50 mg Nuvigil or 100 mg Provigil (modafinil being a 1:1 mixture of (R)-(−)- and (S)-(−)- enantiomers
Teva Reports Top-Line Results from Second Phase III Study of Armodafinil (NUVIGIL®) in Patients with Major Depression Associated with Bipolar 1 Disorder -Following first, positive trial, second ...
This is a list of psychiatric medications used by psychiatrists and other physicians to treat mental illness or distress.. The list is ordered alphabetically according to the condition or conditions, then by the generic name of each medication.
Provigil is a combination of R and S isomers of modafinil. Nuvigil uses only the R isomer, with the hope that it will have longer lasting effects in the body. However, Cephalon states that it has no comparative test data on Nuvigil and Provigil, either on efficacy or patient tolerance. Both substances carry a risk of dependency and producing mania.
Health Risks of Unsafe, Unapproved Enhancement Pills. Unscrupulous business practices are so commonplace in the non-prescription male enhancement pill racket that the FDA actually maintains a list ...
Eugeroics, in the sense of modafinil-type wakefulness promoting agents, include modafinil itself, armodafinil, and adrafinil, among others. [9] They are medically indicated for the treatment of certain sleep disorders , including excessive daytime sleepiness (EDS) in narcolepsy or obstructive sleep apnea (OSA).