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An anxiolytic (/ ˌ æ ŋ k s i ə ˈ l ɪ t ɪ k, ˌ æ ŋ k s i oʊ-/; also antipanic or anti-anxiety agent) [1] is a medication or other intervention that reduces anxiety. This effect is in contrast to anxiogenic agents which increase anxiety. Anxiolytic medications are used for the treatment of anxiety disorders and their related ...
Active metabolites are produced when a person's body metabolizes the drug into compounds that share a similar pharmacological profile to the parent compound and thus are relevant when calculating how long the pharmacological effects of a drug will last. Long-acting benzodiazepines with long-acting active metabolites, such as diazepam and ...
The benzodiazepine class of drugs also interact with peripheral benzodiazepine receptors. Peripheral benzodiazepine receptors are present in peripheral nervous system tissues, glial cells, and to a lesser extent the central nervous system. [182] These peripheral receptors are not structurally related or coupled to GABA A receptors.
Toggle Drug Dependence Therapy subsection. ... Non-Benzodiazepine Anxiolytics. INN Common brand names Buspirone: BuSpar, Spitomin Hydroxyzine: Atarax, Vistaril
Vistaril (hydroxyzine) – an antihistamine for the treatment of itches and irritations, an antiemetic, as a weak analgesic, an opioid potentiator, and as an anxiolytic; Vyvanse (lisdexamfetamine) – a pro-drug stimulant used to treat attention deficit hyperactivity disorder and binge eating disorder; Vyvanse is converted into Dexedrine in vivo
Diazepam, sold under the brand name Valium among others, is a medicine of the benzodiazepine family that acts as an anxiolytic. [14] It is used to treat a range of conditions, including anxiety, seizures, alcohol withdrawal syndrome, muscle spasms, insomnia, and restless legs syndrome. [14]
From there it can be an easy slide into self-medication with drugs or alcohol, or overwork. Thoughts of suicide can beckon. “Definitely a majority” of returning veterans bear some kind of moral injury, said William P. Nash, a retired Navy psychiatrist and a pioneer in stress control and moral injury.
Meprobamate was eventually eclipsed by the benzodiazepines. The target of both categories of anxiotropic compounds is the GABAA receptor. Globally, the two most widely used psychoactive drugs are anxiotropic agents: ethanol, an anxiolytic, and caffeine, an anxiogenic. While intake of both ethanol and caffeine has been shown to exert an ...
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