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  2. Rivaroxaban - Wikipedia

    en.wikipedia.org/wiki/Rivaroxaban

    Using rivaroxaban rather than warfarin costs 70 times more, according to Express Scripts Holding Co, the largest U.S. pharmacy benefits manager. [35] As of 2016, Bayer claimed that the drug was licensed in 130 countries and that more than 23 million patients had been treated. [43]

  3. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    Antistasin, the first discovered naturally occurring direct Xa inhibitor Rivaroxaban, the first synthetic direct Xa inhibitor marketed as a drug Prior to the introduction of direct factor Xa inhibitors, vitamin K antagonists such as warfarin were the only oral anticoagulants for over 60 years, and together with heparin have been the main blood ...

  4. Prescription drug prices in the United States - Wikipedia

    en.wikipedia.org/wiki/Prescription_drug_prices...

    Prescription drug list prices in the United States continually are among the highest in the world. [1] [2] The high cost of prescription drugs became a major topic of discussion in the 21st century, leading up to the American health care reform debate of 2009, and received renewed attention in 2015.

  5. J&J, Bristol Myers lose challenges to US drug price ...

    www.aol.com/news/j-j-bristol-myers-lose...

    The program aims to save $25 billion in drug costs annually by 2031. Industry analysts have said that the negotiated discounts could be steep, ranging from the statutory minimum of 25% to as much ...

  6. Bayer's patent for blood thinner Xarelto invalid, UK ... - AOL

    www.aol.com/news/bayers-patent-blood-thinner...

    Bayer's patent covering its best-selling blood thinner Xarelto is invalid, London's High Court ruled on Friday in a blow to the German drugmaker. The company's blockbuster Xarelto drug generated ...

  7. Andexanet alfa - Wikipedia

    en.wikipedia.org/wiki/Andexanet_alfa

    Andexanet alfa, sold under the brand name Andexxa among others, is an antidote for the medications rivaroxaban and apixaban, when reversal of anticoagulation is needed due to uncontrolled bleeding. [8] It has not been found to be useful for other factor Xa inhibitors. [9] It is given by injection into a vein. [9]

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