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The optic disc appears abnormally small, because not all the optic nerve axons have developed properly. [1] It is often associated with endocrinopathies (hormone deficiencies), developmental delay, and brain malformations. [2] The optic nerve, which is responsible for transmitting visual signals from the retina to the brain, has approximately 1 ...
Developmental delays are more common in children with bilateral optic nerve hypoplasia than those with unilateral optic nerve hypoplasia. [6] Bilateral optic nerve hypoplasia is also associated with a more severe disease course. [7] There may be nystagmus (involuntary eye movements, often side-to-side). [6] In cases of bilateral optic nerve ...
Another condition that produces similar symptoms is a cranial nerve disease. [3] Diagnosis may be made by observing the light reflecting from the person's eyes and finding that it is not centered on the pupil. [3] This is known as the Hirschberg reflex test. Treatment depends on the type of strabismus and the underlying cause. [3]
This disease is a heterogenous group of inherited neuropathies, stemming from a MFN2 mutation, in which both motor and sensory nerves are affected, resulting in distal limb weakness, sensory loss, decreased deep tendon reflexes, and foot deformities. Affected individuals develop progressive optic nerve dysfunction starting later in childhood. [21]
The RGCs axons form the optic nerve. Therefore, the disease can be considered of the central nervous system. [2] Dominant optic atrophy was first described clinically by Batten in 1896 and named Kjer’s optic neuropathy in 1959 after Danish ophthalmologist Poul Kjer, who studied 19 families with the disease. [3] Although dominant optic atrophy ...
People taking Ozempic and Wegovy may be at increased risk of developing a debilitating eye condition that can cause irreversible vision loss, a study published in JAMA Ophthalmology finds.
Leber congenital amaurosis (LCA) is a rare inherited eye disease that appears at birth or in the first few months of life. [2]It affects about 1 in 40,000 newborns. [1] LCA was first described by Theodor Leber in the 19th century.
Two large studies from the University of Southern Denmark suggest that the diabetes medication Ozempic doubles the risk of developing NAION, a rare but serious condition that damages the optic nerve.
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