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In women, low levels of estrogen may cause symptoms such as hot flashes, sleeping disturbances, decreased bone health, [3] and changes in the genitourinary system. Hypoestrogenism is most commonly found in women who are postmenopausal , have primary ovarian insufficiency (POI), or are presenting with amenorrhea (absence of menstrual periods ).
For both men and women, an alternative to testosterone replacement is low-dose clomifene treatment, which can stimulate the body to naturally increase hormone levels while avoiding infertility and other side effects that can result from direct hormone replacement therapy. [24]
The side effects of cyproterone acetate (CPA), a steroidal antiandrogen and progestin, including its frequent and rare side effects, have been studied and characterized.It is generally well-tolerated and has a mild side-effect profile, regardless of dosage, when it used as a progestin or antiandrogen in combination with an estrogen such as ethinylestradiol or estradiol valerate in women.
It is used in hormone therapy for menopausal symptoms and low estrogen levels, hormone therapy for transgender people, and in hormonal birth control. [5] [4] [13] [14] It is also used in the treatment of prostate cancer. [13] The medication is taken by mouth or by injection into muscle or fat once every 1 to 4 weeks. [13] [14]
Upon menopause in females, production of estrogens by the ovaries stops and estradiol levels decrease to very low levels. In addition to its role as a natural hormone, estradiol is used as a medication , for instance in menopausal hormone therapy , and feminizing hormone therapy for transgender women and other genderqueer individuals; for ...
Estradiol benzoate (EB), sold under the brand name Progynon-B among others, is an estrogen medication which is used in hormone therapy for menopausal symptoms and low estrogen levels in women, in hormone therapy for transgender women, and in the treatment of gynecological disorders. [8] [12] [13] It is also used in the treatment of prostate ...
In addition, since the medication suppresses estrogen levels as well, MPA can produce strong functional antiestrogenic effects similarly, and has been used to treat estrogen-dependent conditions such as precocious puberty in girls and endometriosis in women. Due to low estrogen levels, the use of MPA without an estrogen poses a risk of ...
Polyestradiol phosphate (PEP), sold under the brand name Estradurin, is an estrogen medication which is used primarily in the treatment of prostate cancer in men. [1] [9] [2] [10] It is also used in women to treat breast cancer, as a component of hormone therapy to treat low estrogen levels and menopausal symptoms, and as a component of feminizing hormone therapy for transgender women.