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In dogs, the minimum lethal dose of THC is over 3000 mg/kg. [20] According to The Merck Index, [21] the LD 50 of THC (the dose which causes the death of 50% of individuals) is 1270 mg/kg for male rats and 730 mg/kg for female rats from oral consumption in sesame oil, and 42 mg/kg for rats from inhalation. [22]
The time to onset of effects depends strongly on stomach content, but is usually 1 to 2 hours, and may continue for a considerable length of time, whereas the effects of smoking or vaporizing cannabis are almost immediate, lasting a shorter length of time. [10] All of the active constituents enter the body when cannabis is consumed orally.
[4] [5] This means that while its effects are similar to that of Δ 9-THC, it would take more ∆ 8-THC to achieve a comparable level of effect. A 1973 study testing the effects of ∆ 8-THC in dogs and monkeys reported that a single oral dose of 9,000 milligrams per kilogram of body mass (mg/kg) was nonlethal in all dogs and monkeys studied. [6]
A large survey found that 6% of women use cannabis to treat menopause symptoms, such as anxiety and sleep disorders. ... who suggests taking half of the lowest recommended dose of any edible ...
THC was also co-crystallized with autotaxin, deciphering the binding interface of the complex. These results might explain some of the effects of THC on inflammation and neurological diseases, since autotaxin is responsible of LPA generation, a key lipid mediator involved in numerous diseases and physiological processes.
Cannabis (/ ˈ k æ n ə b ɪ s /), [2] commonly known as marijuana (/ ˌ m æ r ə ˈ w ɑː n ə /), [3] weed, and pot, among other names, is a non-chemically uniform drug from the cannabis plant. Native to Central or South Asia, the cannabis plant has been used as a drug for both recreational and entheogenic purposes and in various ...
[14] [15] Studies of chronic cannabis users have demonstrated, although inconsistently, a long-lasting effect on the attention span, memory function, and cognitive abilities of moderate-dose, long-term users. Once cannabis use is discontinued for several months, these effects disappear, unless the user started consuming during adolescence.
Keef. Price: Check your local store Dosage: 10mg Flavors: Mango, Blood Orange, Blackberry Coconut A lot of time spent drinking THC is time spent pretending you are drinking some exclusive luxury ...