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The essential metals for humans are: Sodium, Potassium, Magnesium, Copper, Vanadium, Chromium, Manganese, Iron, Cobalt, Nickel, Zinc, Molybdenum, and Cadmium. Anemia symptoms are caused by lack of a certain essential metal. Anemia can be associated with malnourishment or faulty metabolic processes, usually caused by a genetic defect.
Metallopharmaceutical. A metallopharmaceutical is a drug that contains a metal as an active ingredient. [1][2] Most commonly metallopharmaceuticals are used as anticancer or antimicrobial agents. The efficiency of metallopharmaceuticals is crucially dependent on the respective trace metal binding forms. [3]
In vitro, EDTA, 1,10-phenanthroline and other chelating compounds lower the concentration of metal to the point where the metal is removed from the enzyme active site. Classical lock and key inhibitors such as phosphoramidon and bestatin bind tightly by approximating the transition state of the hydrolysis of the peptide, preventing it from ...
Dimercaprol, also called British anti-Lewisite (BAL), is a medication used to treat acute poisoning by arsenic, mercury, gold, and lead. [3] It may also be used for antimony, thallium, or bismuth poisoning, although the evidence for those uses is not very strong. [3][4] It is given by injection into a muscle. [3]
Thiols are the sulfur analogue of alcohols (that is, sulfur takes the place of oxygen in the hydroxyl (−OH) group of an alcohol), and the word is a blend of " thio- " with "alcohol". Many thiols have strong odors resembling that of garlic or rotten eggs. Thiols are used as odorants to assist in the detection of natural gas (which in pure form ...
Glutathione is capable of preventing damage to important cellular components caused by sources such as reactive oxygen species, free radicals, peroxides, lipid peroxides, and heavy metals. [2] It is a tripeptide with a gamma peptide linkage between the carboxyl group of the glutamate side chain and cysteine.
Nitrous oxide, as medical gas supply, is an inhaled gas used as pain medication, and is typically administered with 50% oxygen mix. It is often used together with other medications for anesthesia. [2] Common uses include during childbirth, following trauma, and as part of end-of-life care. [2]
Chelation therapy is a medical procedure that involves the administration of chelating agents to remove heavy metals from the body. [1] Chelation therapy has a long history of use in clinical toxicology [2] and remains in use for some very specific medical treatments, although it is administered under very careful medical supervision due to various inherent risks, including the mobilization of ...