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  2. Vitamin K - Wikipedia

    en.wikipedia.org/wiki/Vitamin_K

    Vitamin K is a family of structurally similar, fat-soluble vitamers found in foods and marketed as dietary supplements. [1] The human body requires vitamin K for post-synthesis modification of certain proteins that are required for blood coagulation ("K" from Danish koagulation, for "coagulation") or for controlling binding of calcium in bones and other tissues. [2]

  3. Gamma-glutamyl carboxylase - Wikipedia

    en.wikipedia.org/wiki/Gamma-glutamyl_carboxylase

    Gamma-glutamyl carboxylase is an enzyme that catalyzes the posttranslational modification of vitamin K-dependent proteins.Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. [5]

  4. Mevalonate pathway - Wikipedia

    en.wikipedia.org/wiki/Mevalonate_pathway

    The pathway produces two five-carbon building blocks called isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP), which are used to make isoprenoids, a diverse class of over 30,000 biomolecules such as cholesterol, vitamin K, coenzyme Q10, and all steroid hormones.

  5. A vitamin K–rich diet may help protect your health as you age ...

    www.aol.com/finance/vitamin-k-rich-diet-may...

    “Vitamin K is a fat-soluble vitamin, so your body stores it in fat tissue and the liver,” Heather Viola, DO, Primary Care Physician at Mount Sinai Doctors-Ansonia, tells Fortune.

  6. Protein S - Wikipedia

    en.wikipedia.org/wiki/Protein_S

    5627 19128 Ensembl ENSG00000184500 ENSMUSG00000022912 UniProt P07225 Q08761 RefSeq (mRNA) NM_000313 NM_001314077 NM_011173 RefSeq (protein) NP_000304 NP_001301006 NP_035303 Location (UCSC) Chr 3: 93.87 – 93.98 Mb Chr 16: 62.67 – 62.75 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Protein S (also known as PROS) is a vitamin K -dependent plasma glycoprotein synthesized in the ...

  7. Vitamin K reaction - Wikipedia

    en.wikipedia.org/wiki/Vitamin_K_reaction

    VKAs diminish vitamin K levels in the body and inhibit the synthesis of vitamin K dependent clotting factors. [27] Thus, by inhibiting vitamin K, a key element by which the body produces clots, the risk of prolonged bleeding increases. [28] Traditionally, vitamin K has been used as a reversal agent for VKAs.

  8. Coagulation - Wikipedia

    en.wikipedia.org/wiki/Coagulation

    Vitamin K deficiency from other causes (e.g., in malabsorption) or impaired vitamin K metabolism in disease (e.g., in liver failure) lead to the formation of PIVKAs (proteins formed in vitamin K absence), which are partially or totally non-gamma carboxylated, affecting the coagulation factors' ability to bind to phospholipid.

  9. Abetalipoproteinemia - Wikipedia

    en.wikipedia.org/wiki/Abetalipoproteinemia

    This leads to a multiple vitamin deficiency, affecting the fat-soluble vitamin A, vitamin D, vitamin E, and vitamin K. [11] However, many of the observed effects are due to vitamin E deficiency in particular. [11] Acanthocytosis in a patient with abetalipoproteinemia. Signs and symptoms vary and present differently from person to person.