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TOL-463 is an anti-infective medication which is under development for the treatment of bacterial vaginosis (BV) and vulvovaginal candidiasis (VVC) (vaginal yeast infection). [ 3 ] [ 1 ] [ 4 ] [ 2 ] It is a boric acid -based vaginal anti-infective enhanced with ethylenediaminetetraacetic acid (EDTA) which was designed to have improved activity ...
However, a 2016 Cochrane review found high-quality evidence that treating the sexual partners of women with bacterial vaginosis had no effect on symptoms, clinical outcomes, or recurrence in the affected women. It also found that such treatment may lead treated sexual partners to report increased adverse events. [22]
Metronidazole, sold under the brand name Flagyl among others, is an antibiotic and antiprotozoal medication. [10] It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis. [10]
Bacterial vaginosis (BV) is the most common vaginal infection in women. According to the Centers for Disease Control and Prevention (CDC) , the condition affects nearly 30% of women between 15 and ...
Structurally it actually methyl-metronidazole. Effectiveness in the treatment of dientamoebiasis has been reported. [1] It has also been tested against Atopobium vaginae. [2] In the United States, secnidazole is FDA approved for the treatment of bacterial vaginosis and trichomoniasis in adult women. [3]
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