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  2. Glucose uptake - Wikipedia

    en.wikipedia.org/wiki/Glucose_uptake

    Method of glucose uptake differs throughout tissues depending on two factors; the metabolic needs of the tissue and availability of glucose.The two ways in which glucose uptake can take place are facilitated diffusion (a passive process) and secondary active transport (an active process which on the ion-gradient which is established through the hydrolysis of ATP, known as primary active ...

  3. Glycosuria - Wikipedia

    en.wikipedia.org/wiki/Glycosuria

    Glycosuria leads to excessive water loss into the urine with resultant dehydration, a process called osmotic diuresis. Alimentary glycosuria is a temporary condition, when a high amount of carbohydrate is taken, it is rapidly absorbed in some cases where a part of the stomach is surgically removed, the excessive glucose appears in urine ...

  4. Transport maximum - Wikipedia

    en.wikipedia.org/wiki/Transport_maximum

    For example, with glucose, some sugar appears in the urine at levels much lower than 300 mg/dL. [2] The point at which the effects start to appear is called "threshold", and the difference between threshold and transport maximum is called "splay". [3]

  5. Renal glucose reabsorption - Wikipedia

    en.wikipedia.org/wiki/Renal_glucose_reabsorption

    Renal glucose reabsorption is the part of kidney (renal) physiology that deals with the retrieval of filtered glucose, preventing it from disappearing from the body through the urine. If glucose is not reabsorbed by the kidney, it appears in the urine, in a condition known as glycosuria. This is associated with diabetes mellitus. [1]

  6. Renal physiology - Wikipedia

    en.wikipedia.org/wiki/Renal_physiology

    Tubular reabsorption is the process by which solutes and water are removed from the tubular fluid and transported into the blood. It is called reabsorption (and not absorption) both because these substances have already been absorbed once (particularly in the intestines) and because the body is reclaiming them from a postglomerular fluid stream ...

  7. Sodium-glucose transport proteins - Wikipedia

    en.wikipedia.org/wiki/Sodium-glucose_transport...

    SGLT2 inhibitors, also called gliflozins, [14] are used in the treatment of type 2 diabetes. SGLT2 is only found in kidney tubules and in conjunction with SGLT1 resorbs glucose into the blood from the forming urine. By inhibiting SGLT2, and not targeting SGLT1, glucose is excreted which in turn lowers blood glucose levels.

  8. SGLT2 inhibitor - Wikipedia

    en.wikipedia.org/wiki/SGLT2_inhibitor

    The results are decreased kidney reabsorption of glucose, glucosuria effect increases with higher level of glucose in the blood circulation. Therefore, dapagliflozin reduces the blood glucose concentration with a mechanism that is independent of insulin secretion and sensitivity, unlike many other antidiabetic medications .

  9. Glucose transporter - Wikipedia

    en.wikipedia.org/wiki/Glucose_transporter

    In August 1960, in Prague, Robert K. Crane presented for the first time his discovery of the sodium-glucose cotransport as the mechanism for intestinal glucose absorption. [15] Crane's discovery of cotransport was the first ever proposal of flux coupling in biology. [16]

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