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On December 4, 2024, Brian Robert Thompson [4] [5] (born July 10, 1974), the CEO of the US health insurance company UnitedHealthcare, was shot in the back and killed in Midtown Manhattan, New York City. The shooting occurred early in the morning outside an entrance to the New York Hilton Midtown. [6]
The Sackler family is an American family who owned the pharmaceutical company Purdue Pharma and later founded Mundipharma. [1] Purdue Pharma, and some members of the family, have faced lawsuits regarding overprescription of addictive pharmaceutical drugs, including OxyContin.
Fentanyl use has also been associated with aphasia. [60] Despite being a more potent analgesic, fentanyl tends to induce less nausea, as well as less histamine-mediated itching, than morphine. [61] In rare cases, serotonin syndrome is associated with fentanyl use.
Purdue Pharma L.P., formerly the Purdue Frederick Company (1892–2019), was an American privately held pharmaceutical company founded by John Purdue Gray. It was sold to Arthur , Mortimer , and Raymond Sackler in 1952, and then owned principally by the Sackler family and their descendants.
Opioid withdrawal is a set of symptoms (a syndrome) arising from the sudden cessation or reduction of opioids where previous usage has been heavy and prolonged. [1] [2] Signs and symptoms of withdrawal can include drug craving, anxiety, restless legs syndrome, nausea, vomiting, diarrhea, sweating, and an elevated heart rate. Opioid use triggers ...
These include the severity of withdrawal symptoms, the time elapsed since the last opioid use, and the type of opioid involved (long-acting vs. short-acting). [134] A standard induction method involves waiting until the patient exhibits moderate withdrawal symptoms, as measured by a Clinical Opiate Withdrawal Scale, achieving a score of around 12.
Insys Therapeutics Company type Public Traded as Nasdaq: INSY Industry Pharmaceutical Founded 1990 ; 35 years ago (1990) Founder John Kapoor Fate Bankrupt (2019) Headquarters Chandler, Arizona, U.S. Key people Michael Babich (CEO) Products Subsys (fentanyl) Syndros (Tetrahydrocannabinol) Number of employees 343 (2019) Insys Therapeutics was an American specialty pharmaceutical company based in ...
Working with his team, he developed the fentanyl family of drugs and a number of anesthetic agents, including droperidol and etomidate. [6] [7] One of the anti-diarrheal drugs he developed, diphenoxylate , was used in the Apollo program. [8] [9] In 1959, Janssen synthesized the potent opioid fentanyl based on SAR studies of meperidine.