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Hypochlorous acid is the latest popular addition to sensitive and acne-prone skin ... skincare ingredients but should be applied before ... like facial sprays and wound cleansers, Dr. Gohara adds. ...
Clindamycin/tretinoin is a topical gel used in the treatment of acne. The two active ingredients are the antibiotic clindamycin phosphate (1.2%) and tretinoin (0.025%), a retinoid . [ 1 ] The two active ingredients perform different functions, the clindamycin is active against gram-positive bacteria, including streptococci and penicillin ...
Consistency and viscosity affect the adhesion and retention property of the gel, and are important in ensuring the gel is retained at the site of application and effective delivery of the drug. [3] The ingredients in topical gel formulation can be broadly categorized into four types: gelator, solvent, drug, and excipients.
It works by killing acne bacteria that infect skin pores. It also decreases the production of keratin, which is a natural substance that promotes the growth [clarification needed] of acne bacteria. [12] Azelaic acid is also used as a topical gel treatment for rosacea, due to its ability to reduce inflammation. [11]
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Meta-analysis of clinical trials has shown this combined therapy to be more effective than either of its ingredients by themselves. [4]The use of adapalene/benzoyl peroxide in combination with oral antibiotics (lymecycline) has been studied; [5] the combination was well tolerated and showed an improved success rate compared to those receiving only antibiotics (47.6% vs. 33.7%, P = 0.002).
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