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A growing body of research and numerous ... What marijuana really does to your body and brain. ... 11 key findings from one of the most comprehensive reports ever on the health effects of marijuana.
A dried cannabis flower. The short-term effects of cannabis are caused by many chemical compounds in the cannabis plant, including 113 [clarification needed] different cannabinoids, such as tetrahydrocannabinol, and 120 terpenes, [1] which allow its drug to have various psychological and physiological effects on the human body.
Additionally, scientists discovered that participants who were heavy cannabis users also had reduced brain activity in certain areas of the brain, including the dorsolateral prefrontal cortex ...
A larger body of research, though, reveals concerns about the effects of heavy, long-term marijuana use — especially on young people's mental health. ... Many studies show a positive correlation ...
3D model of 2-Arachidonoylglycerol, an endocannaboid. The endocannabinoid system (ECS) is a biological system composed of endocannabinoids, which are neurotransmitters that bind to cannabinoid receptors, and cannabinoid receptor proteins that are expressed throughout the central nervous system (including the brain) and peripheral nervous system.
The Endocannabinoid System (ECS) regulates many functions of the human body. The ECS plays an important role in multiple aspects of neural functions, including the control of movement and motor coordination, learning and memory, emotion and motivation, addictive-like behavior and pain modulation, among others.
D’Souza added that cannabis use can have serious impacts on the developing brain because of its effects on the endocannabinoid system, a complex signaling system in the brain that marijuana targets.
Cnr1 is widely expressed in all major regions of the postnatal day 14 mouse brain, but is conspicuously absent in much of the thalamus. CB1 receptors are expressed most densely in the central nervous system and are largely responsible for mediating the effects of cannabinoid binding in the brain.