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  2. Human vestigiality - Wikipedia

    en.wikipedia.org/wiki/Human_vestigiality

    The muscles connected to the ears of a human do not develop enough to have the same mobility allowed to monkeys. Arrows show the vestigial structure called Darwin's tubercle. In the context of human evolution, vestigiality involves those traits occurring in humans that have lost all or most of their original function through evolution. Although ...

  3. Vestigiality - Wikipedia

    en.wikipedia.org/wiki/Vestigiality

    In humans, the vermiform appendix is sometimes called a vestigial structure as it has lost much of its ancestral digestive function. Vestigiality is the retention, during the process of evolution , of genetically determined structures or attributes that have lost some or all of the ancestral function in a given species. [ 1 ]

  4. Evolution of ageing - Wikipedia

    en.wikipedia.org/wiki/Evolution_of_ageing

    The theory is based on the idea that ageing occurs over time due to the damage of the DNA. As an example, studies of mammalian brain and muscle have shown that DNA repair capability is relatively high during early development when cells are dividing mitotically, but declines substantially as cells enter the post-mitotic state. [28] [29] [30]

  5. Biogerontology - Wikipedia

    en.wikipedia.org/wiki/Biogerontology

    The theory that DNA damage is the primary cause of aging is based, in part, on evidence in human and mouse that inherited deficiencies in DNA repair genes often cause accelerated aging. [ 29 ] [ 30 ] [ 27 ] There is also substantial evidence that DNA damage accumulates with age in mammalian tissues, such as those of the brain, muscle, liver and ...

  6. Atavism - Wikipedia

    en.wikipedia.org/wiki/Atavism

    In such a case, a shift in the time a trait is allowed to develop before it is fixed can bring forth an ancestral phenotype. [5] Atavisms are often seen as evidence of evolution. [6] In social sciences, atavism is the tendency of reversion: for example, people in the modern era reverting to the ways of thinking and acting of a former time.

  7. Genetics of aging - Wikipedia

    en.wikipedia.org/wiki/Genetics_of_aging

    Their study suggests that high levels of iron in the blood likely reduce, and genes involved in metabolising iron likely increase healthy years of life in humans. [13] [12] Ned Sharpless and collaborators demonstrated the first in vivo link between p16-expression and lifespan. [14]

  8. Mutation accumulation theory - Wikipedia

    en.wikipedia.org/wiki/Mutation_accumulation_theory

    In populations where extrinsic mortality is low, the drop in reproductive probability after maturity is less severe than in other cases. The mutation accumulation theory therefore predicts that such populations would evolve delayed senescence. [5] One such example of this scenario can be seen when comparing birds to organisms of equivalent size.

  9. Antagonistic pleiotropy hypothesis - Wikipedia

    en.wikipedia.org/wiki/Antagonistic_pleiotropy...

    Strength of natural selection plot as a function of age. The antagonistic pleiotropy hypothesis (APT) is a theory in evolutionary biology that suggests certain genes may confer beneficial effects early in an organism's life, enhancing reproductive success, while also causing detrimental effects later in life, contributing to the aging process.