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Diabetic retinopathy (also known as diabetic eye disease), is a medical condition in which damage occurs to the retina due to diabetes.It is a leading cause of blindness in developed countries and one of the lead causes of sight loss in the world, even though there are many new therapies and improved treatments for helping people live with diabetes.
ARIA-E refers to cerebral edema, involving the breakdown of the tight endothelial junctions of the blood-brain barrier and subsequent accumulation of fluid. [3] In a double-blind trial of the humanised monoclonal antibody solanezumab (n = 2042), sixteen patients (11 taking the drug, 5 taking a placebo), or 0.78% developed ARIA-E.
Retinal microvascular disease is noninflammatory and resembles that of diabetic retinopathy. This leads to partial or complete vision loss. [6] Headaches due to multiple factors including brain lesions, edema, and papilledema. Mental confusion, loss of cognitive function, loss of memory, slowing of speech and hemiparesis due to brain lesions.
Symptoms of optic neuritis in the affected eye include pain on eye movement, sudden loss of vision, and decrease in color vision (especially reds). Optic neuritis, when combined with the presence of multiple demyelinating white matter brain lesions on MRI, is suspicious for multiple sclerosis.
Diet and lifestyle modification (e.g. low-protein diet in diabetic nephropathy, smoking cessation, weight loss, improved nutrition, and regular exercise). [16] [25] [26] Intensive management of coexisting conditions and risk factors (e.g. adequate control of blood pressure, diabetes and related metabolic abnormalities and lipid management). [25 ...
That’s because type 2 diabetes is the most common type of diabetes, making up 90 to 95 percent of diabetes diagnoses. Type 2 diabetes is caused by something called insulin resistance.
Frequently, retinopathy is an ocular manifestation of systemic disease as seen in diabetes or hypertension. [3] Diabetes is the most common cause of retinopathy in the U.S. as of 2008. [4] Diabetic retinopathy is the leading cause of blindness in working-aged people. [5]
Cardiovascular risk and obesity linked to brain volume loss. High cardiovascular risk and obesity contributed to a gradual reduction in brain volume over several decades, following a bell-shaped ...