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Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacy involved with designing and developing pharmaceutical drugs. Medicinal chemistry involves the identification, synthesis and development of new chemical entities suitable for therapeutic use.
A clinical chemistry analyzer; hand shows size. Clinical chemistry (also known as chemical pathology, clinical biochemistry or medical biochemistry) is a division in medical laboratory sciences focusing on qualitative tests of important compounds, referred to as analytes or markers, in bodily fluids and tissues using analytical techniques and specialized instruments. [1]
Clinical pharmaceutical chemistry is a specialty branch of chemical sciences, which consists of medicinal chemistry with additional training in clinical aspects of translational sciences and medicine.
With worldwide research into pharmacology as well as medicine, traditional medicines or ancient herbal medicines are often translated into modern remedies, such as the anti-malarial group of drugs called artemisinin isolated from Artemisia annua herb, a herb that was known in Chinese medicine to treat fever.
Iatrochemistry (from Ancient Greek ἰατρός (iatrós) 'physician, medicine'; also known as chemiatria or chemical medicine) is an archaic pre-scientific school of thought that was supplanted by modern chemistry and medicine. Having its roots in alchemy, iatrochemistry sought to provide chemical solutions to diseases and medical ailments. [1]
Bioinorganic chemistry is a field that examines the role of metals in biology. Bioinorganic chemistry includes the study of both natural phenomena such as the behavior of metalloproteins as well as artificially introduced metals, including those that are non-essential , in medicine and toxicology .
Metals in medicine are used in organic systems for diagnostic and treatment purposes. [1] Inorganic elements are also essential for organic life as cofactors in enzymes called metalloproteins . When metals are under or over-abundant in the body, equilibrium must be returned to its natural state via interventional and natural methods.
Besides the thalidomide tragedy, another event that raised the importance of issues of stereochemistry in drug research and development was the publication of a manuscript in 1984 entitled, "Stereochemistry, a basis of sophisticated nonsense in pharmacokinetics and clinical pharmacology" by Ariëns. [19]