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The beneficial effects of silicone gel sheeting on the treatment and prevention of these two scars have been confirmed. [10] Since most patients develop hypertrophic and keloid scars within 3 months after surgery or injury, the silicone gel sheeting therapy should be started in the early repair phase to achieve an optimal therapeutic effect.
Silicone scar treatments are commonly used in preventing scar formation and improving existing scar appearance. [50] A meta-study by the Cochrane collaboration found weak evidence that silicone gel sheeting helps prevent scarring. [51] However, the studies examining it were of poor quality and susceptible to bias. [51]
A hypertrophic scar is a cutaneous condition characterized by deposits of excessive amounts of collagen which gives rise to a raised scar, but not to the degree observed with keloids. [1] Like keloids, they form most often at the sites of pimples, body piercings , cuts and burns.
The rubbery, vinegary-smelling silicone caulks, adhesives, and aquarium sealants are also well-known. PDMS is also used as a component in silicone grease and other silicone based lubricants , as well as in defoaming agents , mold release agents , damping fluids, heat transfer fluids, polishes, cosmetics , hair conditioners and other applications.
In its uncured state, silicone rubber is a highly adhesive gel or liquid. To convert it to a solid, it must be cured, vulcanized, or catalyzed.This is normally carried out in a two-stage process at the point of manufacture into the desired shape, and then in a prolonged post-cure process.
It has been developed commercially under the name Integra and is used in massively burned patients, during plastic surgery of the skin, and in treatment of chronic skin wounds. [ 2 ] Alternatively, the term "artificial skin" sometimes is used to refer to skin-like tissue grown in a laboratory, although this technology is still quite a way away ...
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