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Colloid solutions used in intravenous therapy belong to a major group of volume expanders, and can be used for intravenous fluid replacement. Colloids preserve a high colloid osmotic pressure in the blood, [ 50 ] and therefore, they should theoretically preferentially increase the intravascular volume , whereas other types of volume expanders ...
Colloids contain larger insoluble molecules, such as gelatin; blood itself is a colloid. There is no evidence that colloids are better than crystalloids in those who have had trauma, burns, or surgery. Colloids are more expensive than crystalloids. As such, colloids are not recommended for volume expansion in these settings. [2]
Gelofusine is a 4% w/v solution of succinylated gelatine (also known as modified fluid gelatine) used as an intravenous colloid, and behaves much like blood filled with albumins. [2] As a result, it causes an increase in blood volume, blood flow, cardiac output , and oxygen transportation.
Oncotic pressure, or colloid osmotic-pressure, is a type of osmotic pressure induced by the plasma proteins, notably albumin, [1] in a blood vessel's plasma (or any other body fluid such as blood and lymph) that causes a pull on fluid back into the capillary.
Intravenous therapy (abbreviated as IV therapy) is a medical technique that administers fluids, medications and nutrients directly into a person's vein.The intravenous route of administration is commonly used for rehydration or to provide nutrients for those who cannot, or will not—due to reduced mental states or otherwise—consume food or water by mouth.
Hydroxyethyl starch (HES/HAES), sold under the brand name Voluven among others, is a nonionic starch derivative, used as a volume expander in intravenous therapy.The use of HES on critically ill patients is associated with an increased risk of death and kidney problems.
Fluid replacement or fluid resuscitation is the medical practice of replenishing bodily fluid lost through sweating, bleeding, fluid shifts or other pathologic processes. . Fluids can be replaced with oral rehydration therapy (drinking), intravenous therapy, rectally such as with a Murphy drip, or by hypodermoclysis, the direct injection of fluid into the subcutaneous tis
The current understanding of soft matter grew from Albert Einstein's work on Brownian motion, [5] [6] understanding that a particle suspended in a fluid must have a similar thermal energy to the fluid itself (of order of kT). This work built on established research into systems that would now be considered colloids. [7]