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Phenylbiguanide (PBG) is a 5-HT3 agonist used to study the role of 5-HT3 receptors in the central nervous system. [1] It has been found to trigger dopamine release in the nucleus accumbens of rats. [ 2 ]
The mechanism of action of biguanides is not fully understood, and many mechanisms have been proposed for metformin. [citation needed]Biguanides do not affect the output of insulin, unlike other hypoglycemic agents such as sulfonylureas and meglitinides.
1562 – An attempt by François, Duke of Guise, to disperse a church service by Huguenots in Wassy, France, turned into a massacre, resulting in 50 dead, and starting the French Wars of Religion. 1869 – The Russian chemist Dmitri Mendeleev (pictured) finished his design of the first periodic table .
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BMB-201 is a serotonin 5-HT 2A and 5-HT 2C receptor agonist described as a non-hallucinogenic psychoplastogen which is under development for the treatment of depression, anxiety, pain, and other indications.
Phenylisobutylamine, also known as α-ethylphenethylamine (AEPEA) or as butanphenamine (B), is a stimulant drug of the phenethylamine and amphetamine families. [1] [2] [3] It is a higher homologue of amphetamine, differing from amphetamine's molecular structure only by the substitution of the methyl group at the alpha position of the side chain with an ethyl group.
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