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  2. Gamma-glutamyltransferase - Wikipedia

    en.wikipedia.org/wiki/Gamma-glutamyltransferase

    Gamma-glutamyltransferase (also γ-glutamyltransferase, GGT, gamma-GT, gamma-glutamyl transpeptidase; [1] EC 2.3.2.2) is a transferase (a type of enzyme) that catalyzes the transfer of gamma-glutamyl functional groups from molecules such as glutathione to an acceptor that may be an amino acid, a peptide or water (forming glutamate).

  3. Discovery and development of beta2 agonists - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    COPD causes airflow limitations in the lungs because of inflammation. Smoking is the main risk factor but inhalation of toxic and harmful particles and gases can also cause the disease. The symptoms are abnormal mucus production, inflation in the lungs that causes airflow limitation, abnormal gas exchange and pulmonary hypertension.

  4. Beta2-adrenergic agonist - Wikipedia

    en.wikipedia.org/wiki/Beta2-adrenergic_agonist

    Nebulizers continuously deliver aerosolized drug and salbutamol delivered through nebulizer was found to be more effective than IV administration. [10] Salbutamol and terbutaline are also both available in oral forms. [11] In addition, several of these medications are available in intravenous forms, including both salbutamol and terbutaline.

  5. Setanaxib - Wikipedia

    en.wikipedia.org/wiki/Setanaxib

    The study found that patients in stage 3 fibrosis, aka those with baseline liver stiffness levels of 9.6kPa or greater, who were dosed with setanaxib had a 22% reduction in liver stiffness; meanwhile, the patients in this subgroup who received placebo had a 4% increase in liver stiffness.

  6. Mucoactive agent - Wikipedia

    en.wikipedia.org/wiki/Mucoactive_agent

    An expectorant (from the Latin expectorare, to expel or banish) works by signaling the body to increase the amount or hydration of secretions, resulting in more, yet clearer, secretions and lubricating the irritated respiratory tract. [4] One mucoactive agent, guaifenesin, has anxiolytic and muscle-relaxing properties. It is commonly available ...

  7. Heparin - Wikipedia

    en.wikipedia.org/wiki/Heparin

    Heparin production experienced a break in the 1990s. Until then, heparin was mainly obtained from cattle tissue, which was a by-product of the meat industry, especially in North America. With the rapid spread of BSE, more and more manufacturers abandoned this source of supply. As a result, global heparin production became increasingly ...

  8. Pulmonary surfactant - Wikipedia

    en.wikipedia.org/wiki/Pulmonary_surfactant

    Compliance is the ability of lungs and thorax to expand. Lung compliance is defined as the volume change per unit of pressure change across the lung. Measurements of lung volume obtained during the controlled inflation/deflation of a normal lung show that the volumes obtained during deflation exceed those during inflation, at a given pressure.

  9. Fluticasone furoate/umeclidinium bromide/vilanterol - Wikipedia

    en.wikipedia.org/wiki/Fluticasone_furoate/...

    The combination fluticasone furoate/umeclidinium bromide/vilanterol product is approved by the US Food and Drug Administration with an indication for the maintenance treatment of a chronic lung problem called chronic obstructive pulmonary disease (COPD) in adults who (1) have already tried fluticasone furoate/vilanterol (brand name Breo Ellipta) but are still experiencing symptoms of airway ...