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[1] [2] EE is an estrogen, while norethisterone acetate (NETA) is a progestin. [1] It is taken by mouth. [1] Some preparations of EE/NETA used in birth control additionally contain an iron supplement in the form of ferrous fumarate. [3]
Dose Brand names Use NET only: Low (e.g., 0.35 mg) Multiple [a] Progestogen-only oral contraceptive: NET or NETA only: High (e.g., 5 mg, 10 mg) Multiple [b] Gynecological disorders and other uses NETE only: Injection (e.g., 200 mg) Multiple [c] Progestogen-only injectable contraceptive: NET or NETA with ethinylestradiol
[81] [82] [83] [53] [84] A dosage of oral norethisterone of 25 mg/day for 3 weeks in men has been reported to suppress testosterone levels by about 70%, to 100 to 200 ng/dL, within 4 or 5 days, as well as to suppress sperm count and to have no effect on libido or erectile function over this short time period.
Norethisterone and ethinylestradiol levels over 24 hours after a single oral dose of 10 mg NETA in postmenopausal women. [25] NETA metabolizes into ethinylestradiol at a rate of 0.20 to 0.33% across a dose range of 10 to 40 mg. [26] [27] Peak levels of ethinylestradiol with a 10, 20, or 40 mg dose of NETA were 58, 178, and 231 pg/mL, respectively.
All contain an estrogen, ethinylestradiol or mestranol, [1] [2] in varying amounts, and one of a number of different progestogens. (Regarding the estrogen, the inactive 3-methyl ether of ethinylestradiol, which must be metabolized by the liver into the active ethinylestradiol; 50 μg of mestranol is equivalent to only 35 μg of ethinylestradiol and should not be used when high-dose [50 μg ...
Printable version; In other projects Appearance. move to sidebar hide ... Route/form Estrogen Low Standard High Oral: Estradiol: 0.5–1 mg/day: 1–2 mg/day: 2–4 ...
Estrogen: SC implant: 50–200 mg every 6–24 mos Estradiol valerate: Progynova: Estrogen: Oral: 2–10 mg/day Progynova: Estrogen: Sublingual: 1–8 mg/day Delestrogen [c] Estrogen: IM, SC: 2–10 mg/wk or 5–20 mg every 2 wks Estradiol cypionate: Depo-Estradiol: Estrogen: IM, SC: 2–10 mg/wk or 5–20 mg every 2 wks Estradiol dipropionate ...
Levels of estradiol, estrone, and estrone sulfate following a single 2 mg oral dose of estradiol valerate in postmenopausal women. [ 6 ] [ 7 ] [ 8 ] Estradiol levels after a single dose of 2 mg oral estradiol or 2 mg oral estradiol valerate and with continuous administration of 2 mg/day oral estradiol or 2 mg/day oral estradiol valerate (at ...