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Oxybutynin, sold under the brand name Ditropan among others, is an anticholinergic medication primarily used to treat overactive bladder. It is widely considered a first-line therapy for overactive bladder due to its well-studied side effect profile, broad applicability, and continued efficacy over long periods of time.
Sleepiness is uncommon. [10] It is unclear if it is safe in pregnancy. [5] It appears safe in breastfeeding. [11] Greater care is recommended in those with heart problems. [12] It is an anticholinergic agent, [5] which does not have much effect on the brain. [13] Hyoscine butylbromide was patented in 1950, and approved for medical use in 1951. [14]
Otilonium bromide is a drug used to treat abdominal pain caused by irritable bowel syndrome.It is an antispasmodic, which is useful to treat the symptoms of irritable bowel syndrome by reducing abdominal spasms (), bloating, pain, and gut motility.
Tolterodine, although it acts on all types of receptors, has fewer side effects than oxybutynin (M 3 and M 1 selective, but more so in the parotid than in the bladder) as tolterodine targets the bladder more than other areas of the body. [medical citation needed]
In children between 11 and 16, the extended-release formulation is FDA-approved for the relief of cancer pain, trauma pain, or pain due to major surgery (for those already treated with opioids, who can tolerate at least 20 mg per day of oxycodone) – this provides an alternative to Duragesic , the only other extended-release opioid analgesic ...
Etodolac is generally avoided during pregnancy and nursing.NSAIDs may cause adverse cardiovascular effects in the fetus during pregnancy. [3]In October 2020, the U.S. Food and Drug Administration (FDA) required the drug label to be updated for all nonsteroidal anti-inflammatory medications to describe the risk of kidney problems in unborn babies that result in low amniotic fluid.
[9] [10] In addition to the α 1A-adrenergic receptor, nicergoline is an antagonist of the serotonin 5-HT 1A receptor (IC 50 = 6 nM) and shows moderate affinity for serotonin 5-HT 2 and α 2-adrenergic receptors and low affinity for the dopamine D 1 and D 2 and muscarinic acetylcholine M 1 and M 2 receptors. [2]
Propantheline is one of a group of antispasmodic medications which work by blocking the action of the chemical messenger acetylcholine, which is produced by nerve cells, to muscarinic receptors present in various smooth muscular tissues, in places such as the gut, bladder and eye.
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