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Hairy cell leukemia is an uncommon hematological malignancy characterized by an accumulation of abnormal B lymphocytes. [1] The incidence of hairy cell leukemia (HCL) is 0.28-0.30 cases per 100,000 people in Europe and the United States and the prevalence is 3 cases per 100,000 in Europe with a lower prevalence in Asia, Africa and the Middle East.
Moxetumomab pasudotox, sold under the brand name Lumoxiti, is an anti-CD22 immunotoxin medication for the treatment of adults with relapsed or refractory hairy cell leukemia (HCL) who have received at least two prior systemic therapies, including treatment with a purine nucleoside analog.
John Moore first visited UCLA Medical Center on October 5, 1976, after he was diagnosed with hairy cell leukemia.Physician and cancer researcher David Golde took samples of Moore's blood, bone marrow, and other bodily fluids to confirm the diagnosis and recommended a splenectomy because of the potentially fatal amount of swelling in Moore's spleen. [3]
Large granular lymphocytic leukemia may involve either T-cells or NK cells; like hairy cell leukemia, which involves solely B cells, it is a rare and indolent (not aggressive) leukemia. [26] Adult T-cell leukemia is caused by human T-lymphotropic virus (HTLV), a virus similar to HIV. Like HIV, HTLV infects CD4+ T-cells and replicates within ...
Continuing her research with hairy cell leukemia, Bouroncle worked with Ohio State investigators Michael Grever and Eric Kraut in the 1980s to develop a treatment for the disease known as deoxycoformycin. [4] She helped to found The James Cancer Hospital, which opened at Ohio State in 1990. She won several teaching-related awards at Ohio State. [1]
The Childhood Leukemia Foundation (CLF) filed a lawsuit against the U.S. Federal Trade Commission (FTC) on Friday, asking a court to stop an investigation into whether it spent more than 90% of ...
Here are links to possibly useful sources of information about Hairy cell leukemia. PubMed provides review articles from the past five years (limit to free review articles) The TRIP database provides clinical publications about evidence-based medicine. Other potential sources include: Centre for Reviews and Dissemination and CDC
Honey, a popular browser extension owned by PayPal, is the target of one YouTuber's investigation that was widely shared over the weekend—over 6 million views in just two days. The 23-minute ...