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Ciprofloxacin is weakly bound to serum proteins (20–40%). It is an inhibitor of the drug-metabolizing enzyme cytochrome P450 1A2, which leads to the potential for clinically important drug interactions with drugs metabolized by that enzyme. [5] Ciprofloxacin is about 70% available when administered orally. [3]
The following is a list of medications associated with DIAM. Nonsteroidal anti-inflammatory drugs (NSAIDs) [1] Biologic drugs such as intravenous immunoglobulin (IVIG). [1] Antibiotics such as sulfonamides, isoniazid, ciprofloxacin, penicillin [2] Antiepileptic drugs such as Carbamazepine and Lamotrigine [2] Phenazopyridine [2]
"abdominal pain, diarrhea, potentially carcinogenic, with others can potentiate cardiac glycosides and antiarrhythmic agents", [3] liver damage [3] St John's wort: Tipton's weed, Klamath weed Hypericum perforatum: Photosensitization, [3] [15] GI disturbances, "allergic reactions, fatigue, dizziness, confusion, dry mouth" [15] Valerian
In this condition vertigo can last for days. [2] More severe causes should also be considered, [9] especially if other problems such as weakness, headache, double vision, or numbness occur. [2] Dizziness affects approximately 20–40% of people at some point in time, while about 7.5–10% have vertigo. [3] About 5% have vertigo in a given year ...
Each episode of vertigo typically lasts less than one minute. [3] Nausea is commonly associated. [7] BPPV is one of the most common causes of vertigo. [1] [2] [8] BPPV is a type of balance disorder along with labyrinthitis and Ménière's disease. [3] It can result from a head injury or simply occur among those who are older. [3]
Antibiotics such as metronidazole, tinidazole, cephamandole, latamoxef, cefoperazone, cefmenoxime, and furazolidone, cause a disulfiram-like chemical reaction with alcohol by inhibiting its breakdown by acetaldehyde dehydrogenase, which may result in vomiting, nausea, and shortness of breath. [11]
Neurologic disorders tend to cause constant vertigo or disequilibrium and usually have other symptoms of neurologic dysfunction associated with the vertigo. Many medications used to treat seizures, depression, anxiety, and pain affect the vestibular system and the central nervous system which can cause the symptom of disequilibrium. [21]
The side effects of penicillin can be altered by taking other medications at the same time. Taking oral contraceptives along with penicillin may lower the effects of the contraceptive. When probenecid is used concurrently with penicillin, kidney excretion of probenecid is decreased resulting in higher blood levels of penicillin in the circulation.
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