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Thrombin (Factor IIa) (EC 3.4.21.5, fibrose, thrombase, thrombofort, topical, thrombin-C, tropostasin, activated blood-coagulation factor II, E thrombin, beta-thrombin, gamma-thrombin) is a serine protease, that converts fibrinogen into strands of insoluble fibrin, as well as catalyzing many other coagulation-related reactions.
Pender's health promotion model theory was first published in 1982 and later revised in 1996 and 2002. It is used for nursing research, education, and practice. Research has been conducted on the model since its inception. 250 articles have been published in the English language that use or apply Pender's HPM. [ 6 ]
Prothrombin G20210A is a genotypic trait that provides a prompter coagulation response. It increases the risk of blood clots including from deep vein thrombosis , and of pulmonary embolism . [ 1 ] One copy of the mutation increases the risk of a blood clot from 1 in 1,000 per year to 2.5 in 1,000. [ 1 ]
Coagulation activation markers are biomarkers of net activation of coagulation and fibrinolysis. [ 1 ] [ 2 ] Examples include prothrombin fragment 1+2 (F1+2), thrombin–antithrombin complex (TAT), fibrinopeptide A (FpA), fibrin monomers (FMs), plasmin-α 2 -antiplasmin complex (PAP), activated protein C–protein C inhibitor (APC-PCI), and D ...
Coagulation factor concentrates are used to treat hemophilia, to reverse the effects of anticoagulants, and to treat bleeding in people with impaired coagulation factor synthesis or increased consumption. Prothrombin complex concentrate, cryoprecipitate and fresh frozen plasma are commonly used coagulation factor products.
Typically, dementia is associated with classic symptoms like confusion and memory loss. But new research finds that there could be a less obvious risk factor out there: your cholesterol levels ...
Suspects discovered by police in Edge at Lowry Apartments. During the torture, the armed individuals went back to the man and woman's apartment and burglarized it, Chamberlain said.
Platelet factor 4 can cause heparin-induced thrombocytopenia. The package insert states that prothrombin complex concentrate is contraindicated in patients with disseminated intravascular coagulation, a pathological activation of coagulation, [24] because giving clotting factors would only further fuel this process. However, if the PCC is given ...