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In 1992 it was removed from the market and manufacturing ceased. During this time low molecular weight iron dextran was introduced and released for clinical use in 1992. [4] The use of low molecule weight iron dextran was common place for renal dialysis patients and due to its success usage increased progressively through to 1997. [4]
Iron preparation is the formulation for iron supplements indicated in prophylaxis and treatment of iron-deficiency anemia. Examples of iron preparation include ferrous sulfate, ferrous gluconate, and ferrous fumarate. It can be administered orally, and by intravenous injection, or intramuscular injection. [1] Early Iron Supplement for Anemia
Iron can be supplemented by mouth using various forms, such as iron(II) sulfate. This is the most common and well studied soluble iron salt sold under brand names such as Feratab, Fer-Iron, and Slow-FE. It is in complex with gluconate, dextran, carbonyl iron, and other salts.
ATC code B03 Antianemic preparations is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
Dextran is a complex branched glucan (polysaccharide derived from the condensation of glucose), originally derived from wine. IUPAC defines dextrans as "Branched poly-α-d-glucosides of microbial origin having glycosidic bonds predominantly C-1 → C-6". [ 1 ]
It replaced iron dextran, which had been in use in the US since the 1900s, as a treatment for iron deficiency. Iron dextran was only used for extremely high risk situations, because it released enough iron at once to be toxic to the body. Further development of iron dextran was able to lower these reactions, but also caused more severe ...
Dextran 70 is a type of fluid given by injection into a vein to expand blood volume. [1] Specifically it is used for shock such as that caused by bleeding or burns when blood transfusions are not quickly available. [2] However, it does not carry oxygen. [2] Common side effects include vomiting, fever, and joint pains. [2]
Iron(III)-hydroxide polymaltose complex is a medication used to treat iron deficiency / iron deficiency anemia and belongs to the group of oral iron preparations.The preparation is a macromolecular complex, consisting of iron(III) hydroxide (trivalent iron, Fe 3+, Fe(OH) 3 ·H 2 O) and the carrier polymaltose and is available in solid form as a film-coated or chewable tablet and in liquid form ...
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