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An antipyretic (/ ˌ æ n t i p aɪ ˈ r ɛ t ɪ k /, from anti-'against' and pyretic 'feverish') is a substance that reduces fever. [1] Antipyretics cause the hypothalamus to override a prostaglandin-induced increase in temperature. [citation needed] The body then works to lower the temperature, which results in a reduction in fever.
Hyperthermia requires treatment. [2] Fever is one of the most common medical signs. [2] It is part of about 30% of healthcare visits by children [2] and occurs in up to 75% of adults who are seriously sick. [11] While fever evolved as a defense mechanism, treating a fever does not appear to improve or worsen outcomes.
Pyrotherapy (artificial fever) is a method of treatment by raising the body temperature or sustaining an elevated body temperature using a fever. In general, the body temperature was maintained at 41 °C (105 °F). [1] Many diseases were treated by this method in the first half of the 20th century.
Paracetamol, [a] or acetaminophen, [b] is a non-opioid analgesic and antipyretic agent used to treat fever and mild to moderate pain. [13] [14] [15] It is a widely available over-the-counter drug sold under various brand names, including Tylenol and Panadol.
Example of some 200 mg ibuprofen tablets A 150 ml bottle (100 mg/5 ml dosage) of ibuprofen, sold in Greece. Ibuprofen is used primarily to treat fever (including postvaccination fever), mild to moderate pain (including pain relief after surgery), painful menstruation, osteoarthritis, dental pain, headaches, and pain from kidney stones.
Aminophenazone was first synthesized by Friedrich Stolz and Ludwig Knorr in the late nineteenth century, and sold as an anti-fever medicine known as Pyramidon by Hoechst AG from 1897 until its eventual replacement [when?] by the safer propyphenazone molecule.
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