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Sensitization is a non-associative learning process in which repeated administration of a stimulus results in the progressive amplification of a response. [1] Sensitization often is characterized by an enhancement of response to a whole class of stimuli in addition to the one that is repeated.
Reverse tolerance or drug sensitization is a pharmacological phenomenon describing subjects' increased reaction (positive or negative) to a drug following its repeated use. [4] Not all drugs are subject to reverse tolerance. This is the opposite of drug tolerance, in which the effect or the subject's reaction decreases following its repeated ...
drug sensitization or reverse tolerance – the escalating effect of a drug resulting from repeated administration at a given dose; drug withdrawal – symptoms that occur upon cessation of repeated drug use; physical dependence – dependence that involves persistent physical–somatic withdrawal symptoms (e.g., fatigue and delirium tremens)
Once a bacterium has been identified following microbiological culture, antibiotics are selected for susceptibility testing. [5] Susceptibility testing methods are based on exposing bacteria to antibiotics and observing the effect on the growth of the bacteria (phenotypic testing), or identifying specific genetic markers (genetic testing). [6]
The response to the antigen occurs in two stages: the sensitization and the effect stage. In the "sensitization" stage, the host experiences an asymptomatic contact with the antigen. Subsequently, in the "effect" period, the pre-sensitized host is re-introduced to the antigen, which then leads to a type I anaphylactic or atopic immune response ...
In clinical pharmacology, a potentiator is a drug, herb, or chemical that intensifies the effects of a given drug. For example, hydroxyzine or dextromethorphan is used to get more pain relief and anxiolysis out of an equal dose of an opioid medication. The potentiation can take place at any part of the liberation, absorption, distribution ...
[3] [4] Similar to binge drinkers, individuals suffering from alcohol dependence develop changes to neurotransmitter systems, which occur as a result of kindling and sensitization during withdrawal. This progressively lowers the threshold needed to cause alcohol-related brain damage and cognitive impairments, leading to altered neurological ...
The first two groups receive the evaluation test before and after the study, as in a normal two-group trial. The second groups receive the evaluation only after the study. [citation needed] The effectiveness of the treatment can be evaluated by comparisons between groups 1 and 3 and between groups 2 and 4. [citation needed]. In addition, the ...