Search results
Results from the WOW.Com Content Network
Physical and chemical properties of the drug. The physical properties are solid, liquid and gas. The chemical properties are solubility, stability, pH, irritancy etc. Site of desired action: the action may be localised and approachable or generalised and not approachable. Rate of extent of absorption of the drug from different routes.
Skin absorption relates to the degree of exposure to and possible effect of a substance which may enter the body through the skin. Human skin comes into contact with many agents intentionally and unintentionally. Skin absorption can occur from occupational, environmental, or consumer skin exposure to chemicals, cosmetics, or pharmaceutical ...
The amount of topical drug molecules being delivered to the skin is affected solely by the physicochemical properties of the topical drug. [1] The first factor is the weight of the drug molecule. The smaller of the drug molecular weight or particle size, the higher rate of its diffusion and absorption into the skin.
Meaning Origin language and etymology Example(s) juxta-near to, alongside, or next to Latin iuxta: juxtaglomerular apparatus: kal-potassium: New Latin kalium, potassium hyperkalemia: kary-[3] nucleus Greek κάρυον (káruon), nut eukaryote: kerat-[4] cornea (eye or skin) Greek κέρας (kéras), horn keratoscope: kine-[5] movement
A transdermal patch is classified by the U.S. Food and Drug Administration as a combination product, consisting of a medical device combined with a drug or biological product that the device is designed to deliver. Prior to sale in the United States, any transdermal patch product must apply for and receive approval from the Food and Drug ...
In cases of short duration, there may be small blisters, while in long-term cases the skin may become thickened. [149] The area of skin involved can vary from small to the entire body. [149] [150] Diagnosis – Medical diagnosis (abbreviated Dx [151] or D S) is the process of determining which disease or condition explains a person's symptoms ...
Absorption is a primary focus in drug development and medicinal chemistry, since a drug must be absorbed before any medicinal effects can take place. Moreover, the drug's pharmacokinetic profile can be easily and significantly changed by adjusting factors that affect absorption.
Physical properties of the drug (hydrophobicity, pKa, solubility) The drug formulation (immediate release, excipients used, manufacturing methods, modified release – delayed release, extended release, sustained release, etc.) Whether the formulation is administered in a fed or fasted state; Gastric emptying rate; Circadian differences