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Amyloidosis (am-uh-loi-DO-sis) is a rare disease that occurs when a protein called amyloid builds up in organs. This amyloid buildup can make the organs not work properly. Organs that may be affected include the heart, kidneys, liver, spleen, nervous system and digestive tract.
Amyloidosis is often overlooked because the signs and symptoms can mimic those of more-common diseases. Early diagnosis can help prevent further organ damage. Precise diagnosis is important because treatment varies greatly, depending on your specific condition.
Amyloidosis (am-uh-loi-DO-sis) is a rare disease that occurs when a substance called amyloid builds up in your organs. Amyloid is an abnormal protein that is produced in your bone marrow and can be deposited in any tissue or organ.
Learn about how our experts help people with cardiac amyloidosis, a serious condition of adults that hinders the heart's blood-pumping function.
At Mayo Clinic, your team of specialists is experienced in diagnosing and treating amyloidosis. Your doctors will work together across disciplines to provide you with a precise diagnosis and a treatment plan for your specific needs that is designed to preserve organ function and manage symptoms.
Dr. Martha Grogan, a Mayo Clinic cardiologist and director of the Cardiac Amyloid Clinic at Mayo Clinic in Rochester, Minnesota, explains what cardiac amyloidosis is, why knowing the type of amyloid is key to treatment, and what's on the horizon to help patients with this rare condition.
Amyloidosis is a rare disease that can be difficult to diagnose. Mayo Clinic specialists use the latest technology, such as mass spectrometry and specialized imaging, to pinpoint the type of amyloidosis you have. That information is important in determining the most effective treatment for you.
Alzheimer's disease is the biological process that begins with the appearance of a buildup of proteins in the form of amyloid plaques and neurofibrillary tangles in the brain. This causes brain cells to die over time and the brain to shrink.
JACKSONVILLE, Fla. — Mayo Clinic researchers led a laboratory study that found a new way to prevent the accumulation of amyloid plaque – a key feature of Alzheimer’s disease – by eliminating a class of molecules called heparan sulfates that form on brain cells.
Some of the new Alzheimer's treatments target clumps of the protein beta-amyloid, known as plaques, in the brain. Plaques are a characteristic sign of Alzheimer's disease. Strategies aimed at beta-amyloid include: Recruiting the immune system. Medicines known as monoclonal antibodies may prevent beta-amyloid from clumping into plaques.