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Hydromorphone is a semi-synthetic μ-opioid agonist. As a hydrogenated ketone of morphine, it shares the pharmacologic properties typical of opioid analgesics. Hydromorphone and related opioids produce their major effects on the central nervous system and gastrointestinal tract.
Side effects. Common side effects of hydrocodone are nausea, vomiting, constipation, drowsiness, dizziness, lightheadedness, anxiety, abnormally happy or sad mood, dry throat, difficulty urinating, rash, itching, and contraction of the pupils. Serious side effects include slowed or irregular breathing and chest tightness.
Oxycodone/naloxone. Oxycodone/naloxone, sold under the brand name Targin among others, is a combination pain medication. It is available as modified-release tablets and is taken by mouth. [5] The oxycodone component is an opioid and is responsible for the pain-relieving effects. Naloxone opposes the effects of opioids but is poorly absorbed ...
Main side effects of oxycodone [ 43 ] Two tablets (10 mg) of oxycodone and safety blisters. Most common side effects of oxycodone include reduced sensitivity to pain, delayed gastric emptying, euphoria, anxiolysis (a reduction in anxiety), feelings of relaxation, and respiratory depression. [ 44 ]
Common side effects include dizziness, sleepiness, constipation, and vomiting. [1] [3] Serious side effects include addiction, decreased rate of breathing, low blood pressure, severe allergic reactions, and liver failure. [1] Use during pregnancy may harm the fetus. [1] Use with alcohol is not recommended. [3]
This requires them to increase their drug dosage to maintain the benefit, and that in turn also increases the unwanted side effects. [72] Long-term opioid use can cause opioid-induced hyperalgesia, which is a condition in which the patient has increased sensitivity to pain. [95] All of the opioids can cause side effects. [64]
troublesome side effects of oral morphine, hydromorphone, or oxycodone. [49] [50] When using the transdermal patch, patients must be careful to minimize or avoid external heat sources (direct sunlight, heating pads, etc.), which can trigger the release and absorption of too much medication and cause potentially deadly complications. [51]
Potentially serious side effects of morphine include decreased respiratory effort, vomiting, nausea, and low blood pressure. [12] Morphine is addictive and prone to abuse. [12] If one's dose is reduced after long-term use, opioid withdrawal symptoms may occur. [12] Common side effects of morphine include drowsiness, vomiting, and constipation. [12]
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