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Sample size determination or estimation is the act of choosing the number of observations or replicates to include in a statistical sample. The sample size is an important feature of any empirical study in which the goal is to make inferences about a population from a sample. In practice, the sample size used in a study is usually determined ...
The MSE either assesses the quality of a predictor (i.e., a function mapping arbitrary inputs to a sample of values of some random variable), or of an estimator (i.e., a mathematical function mapping a sample of data to an estimate of a parameter of the population from which the data is sampled).
It is remarkable that the sum of squares of the residuals and the sample mean can be shown to be independent of each other, using, e.g. Basu's theorem.That fact, and the normal and chi-squared distributions given above form the basis of calculations involving the t-statistic:
However, those formulas do not tell us how precise the estimates are, i.e., how much the estimators ^ and ^ vary from sample to sample for the specified sample size. Confidence intervals were devised to give a plausible set of values to the estimates one might have if one repeated the experiment a very large number of times.
In bioinformatics, the root mean square deviation of atomic positions is the measure of the average distance between the atoms of superimposed proteins. In structure based drug design, the RMSD is a measure of the difference between a crystal conformation of the ligand conformation and a docking prediction.
Bessel's correction. In statistics, Bessel's correction is the use of n − 1 instead of n in the formula for the sample variance and sample standard deviation, [1] where n is the number of observations in a sample. This method corrects the bias in the estimation of the population variance. It also partially corrects the bias in the estimation ...
Bartlett's test is used to test the null hypothesis, H0 that all k population variances are equal against the alternative that at least two are different. If there are k samples with sizes and sample variances then Bartlett's test statistic is. where and is the pooled estimate for the variance. The test statistic has approximately a distribution.