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Leptospirosis is a blood infection caused by the bacterium Leptospira [8] that can infect humans, dogs, rodents and many other wild and domesticated animals. [8] Signs and symptoms can range from none to mild ( headaches , muscle pains , and fevers ) to severe ( bleeding in the lungs or meningitis ). [ 5 ]
This includes mostly drug-induced hepatotoxicity, (DILI) which may generate many different patterns over liver disease, including . cholestasis; necrosis; acute hepatitis and chronic hepatitis of different forms,
Leptospira (from Ancient Greek λεπτός (leptós) 'fine, thin, narrow, etc.' and Latin spira 'coil') [1] is a genus of spirochaete bacteria, including a small number of pathogenic and saprophytic species. [2]
Leptospirosis is treated in humans by the antibiotics penicillin and doxycycline. [7] [8] L. interrogans has many properties that ensure its optimal survival in specific conditions, including two periplasmic flagella for movement and mobility. These flagella enable L. interrogans to more easily access and infect both human and mammalian tissues ...
Leptospirosis: Caused by bacterium of genus Leptospira: Water contaminated by the animal urine carrying the bacteria Begins with flu-like symptoms then resolves. The second phase then occurs involving meningitis, liver damage (causes jaundice), and kidney failure: Otitis Externa (swimmer's ear) Caused by a number of bacterial and fungal species.
Leptospira noguchii is another pathogenic bacteria that causes Leptospirosis. Leptospirosis can be transferred in a multitude of ways. Leptospirosis can transfer from animals to humans , humans to humans, or animals to animals via intake of contaminated body fluids, such as urine and blood. [7]
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Conjunctival suffusion is an eye finding occurring early in leptospirosis, which is caused by Leptospira interrogans.Conjunctival suffusion is characterized by redness of the conjunctiva that resembles conjunctivitis, but it does not involve inflammatory exudates. [1]