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Some people with diverticulosis complain of symptoms such as cramping, bloating, flatulence, and irregular defecation. However, it is unclear if these symptoms are attributable to the underlying diverticulosis or to coexistent irritable bowel syndrome. [7] Diverticular disease was found associated with a higher risk of left sided colon cancer. [8]
NSAIDs and Aspirin use – these drugs have been shown to increase risk of diverticular bleeding and diverticulitis complications such as diverticular perforation. [10] Genetics – over 30 susceptibility loci have been identified for diverticular disease, [11] including ARHGAP15, COLQ, and FAM155A. [12]
Pattern B has an appearance similar to mild-to moderate ulcerative colitis (30.40%), whereas pattern C appears similar to Crohn's disease (10.90%). [2] Pattern D is the least common, and appears similar to severe ulcerative colitis (6.50%). [2] SCAD is diagnosed by colonoscopy.
About 10% of cases have a more serious cause including gallbladder (gallstones or biliary dyskinesia) or pancreas problems (4%), diverticulitis (3%), appendicitis (2%) and cancer (1%). [2] More common in those who are older, ischemic colitis , [ 5 ] mesenteric ischemia , and abdominal aortic aneurysms are other serious causes.
Left-sided diverticular disease (involving the sigmoid colon) is most common in the West, while right-sided diverticular disease (involving the ascending colon) is more common in Asia and Africa. [8] Among people with diverticulosis, 4–15% may go on to develop diverticulitis.
Epiploic appendagitis presents with an acute onset of pain, commonly in the left lower quadrant the symptoms often lead to a misdiagnosis for diverticulitis. Diverticulitis manifests with evenly distributed lower abdominal pain accompanied with nausea, fever, and leukocytosis. Patients with acute epiploic appendagitis do not normally report a ...
Symptoms of ischemic colitis vary depending on the severity of the ischemia. The most common early signs of ischemic colitis include abdominal pain (often left-sided), with mild to moderate amounts of rectal bleeding. [11] The sensitivity of findings among 73 patients were: [12] abdominal pain (78%) lower gastrointestinal tract bleeding (62%)
Attempts at removal can have severe and even lethal effects, such as the rupture of the colon wall by catheter or an acute angle of the fecaloma (stercoral perforation), followed by sepsis. It may also lead to stercoral perforation, a condition characterized by bowel perforation due to pressure necrosis from a fecal mass or fecaloma.