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15277 Ensembl ENSG00000159399 ENSMUSG00000000628 UniProt P52789 O08528 RefSeq (mRNA) NM_000189 NM_001371525 NM_013820 RefSeq (protein) NP_000180 NP_001358454 NP_038848 Location (UCSC) Chr 2: 74.83 – 74.89 Mb Chr 6: 82.7 – 82.75 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Hexokinase II, also known as Hexokinase B and HK2, is an enzyme which in humans is encoded by the HK2 gene ...
This is because phosphorylated hexoses are charged, and thus more difficult to transport out of a cell. In patients with essential fructosuria , metabolism of fructose by hexokinase to fructose-6-phosphate is the primary method of metabolizing dietary fructose; this pathway is not significant in normal individuals.
The cell cycle is a series of complex, ordered, sequential events that control how a single cell divides into two cells, and involves several different phases. The phases include the G1 and G2 phases, DNA replication or S phase, and the actual process of cell division, mitosis or M phase. [ 1 ]
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The Sd.Kfz.2 (German: Sonderkraftfahrzeug 2) is a half-track motorcycle with a single front wheel, better known as the Kleines Kettenkraftrad HK 101 (from German klein ' small ' Ketten ' chains/tracks ' and Kraftrad ' motorcycle '), shortened to Kettenkrad (pl. Kettenkräder). It was used by the military of Nazi Germany during the Second World War.
Steps of the cell cycle. The restriction point occurs between the G 1 and S phases of interphase.. The restriction point (R), also known as the Start or G 1 /S checkpoint, is a cell cycle checkpoint in the G 1 phase of the animal cell cycle at which the cell becomes "committed" to the cell cycle, and after which extracellular signals are no longer required to stimulate proliferation. [1]
Geminin, DNA replication inhibitor, also known as GMNN, is a protein in humans encoded by the GMNN gene. [5] A nuclear protein present in most eukaryotes and highly conserved across species, numerous functions have been elucidated for geminin including roles in metazoan cell cycle, cellular proliferation, cell lineage commitment, and neural differentiation. [6]
Whether homologous recombination or NHEJ is used to repair double-strand breaks is largely determined by the phase of cell cycle. Homologous recombination repairs DNA before the cell enters mitosis (M phase). It occurs during and shortly after DNA replication, in the S and G 2 phases of the cell cycle, when sister chromatids are more easily ...