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The tendency to develop a lipoma is not necessarily hereditary, although hereditary conditions such as familial multiple lipomatosis might include lipoma development. [ 15 ] [ 16 ] Genetic studies in mice have shown a correlation between the HMG I-C gene (previously identified as a gene related to obesity) and lipoma development.
Familial multiple lipomatosis is a hereditary adipose tissue disorder that is characterized by the formation of multiple lipomas that occur in a particular distribution. [1] The lipomas are well-encapsulated, slow-growing, benign fatty tumors. The distribution is defined as being focused in the trunk of the body and extremities. [2]
In 1993, a genetic polymorphism within lipomas was localized to chromosome 12q15, where the HMGIC gene encodes the high-mobility-group protein isoform I-C. [2] This is one of the most commonly found mutations in solitary lipomatous tumors but lipomas often have multiple mutations. Reciprocal translocations involving chromosomes 12q13 and 12q14 ...
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Lipomas affect about 1% of the population, with no documented sex bias, and about 1 in every 1000 people will have a lipoma within their lifetime. [25] [26] The cause of lipomas is not well defined. Genetic or inherited causes of lipomas play a role in around 2-3% of patients. [25]
The tendency to develop a lipoma is not necessarily hereditary, although it is in a syndrome like familial multiple lipomatosis (where more than one lipoma develops over time.)[11] Hereditary lipomatosis is an autosomal dominant disorder and is a rare condition.[12]
Hibernoma (fetal lipoma, lipoma of embryonic fat, lipoma of immature adipose tissue) Hypertrophic scar; Immunosuppression-associated Kaposi sarcoma; Infantile digital fibromatosis (inclusion body fibromatosis, infantile digital myofibroblastoma, Reye tumor) Infantile hemangiopericytoma (congenital hemangiopericytoma)
The employee, who was not named, was fired from her position, Administrator Deanne Criswell said in a post to social media on Saturday.