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  2. Genetics of Down syndrome - Wikipedia

    en.wikipedia.org/wiki/Genetics_of_Down_syndrome

    Mitotic nondisjunction after conception would lead to mosaicism, and is discussed later. Some cases have been reported of people with Down syndrome having children with trisomy 21. [5] In these cases (all from mothers), the ovaries were trisomy 21, leading to a secondary nondisjunction during gametogenesis and a gamete with an extra chromosome 21.

  3. Down syndrome - Wikipedia

    en.wikipedia.org/wiki/Down_syndrome

    Down syndrome or Down's syndrome, [12] also known as trisomy 21, is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21. [3] It is usually associated with developmental delays, mild to moderate intellectual disability, and characteristic physical features.

  4. Trisomy - Wikipedia

    en.wikipedia.org/wiki/Trisomy

    Karyotype of a human with Trisomy 21 (Down syndrome). Trisomies can occur with any chromosome, but often result in miscarriage rather than live birth.For example, Trisomy 16 is most common in human pregnancies, occurring in more than 1%, but the only surviving embryos are those having some normal cells in addition to the trisomic cells (mosaic trisomy 16). [3]

  5. Everything you need to know about Down syndrome - AOL

    www.aol.com/news/everything-know-down-syndrome...

    Most of the time, Down syndrome is not inherited. Instead, it is caused by abnormal cell division. These chromosomal abnormalities are much more prevalent in mothers of advanced maternal age ...

  6. A mom of 3 learned she had mosaic Down syndrome through ... - AOL

    www.aol.com/lifestyle/mom-3-learned-she-had...

    For Ashley Zambelli, a surprise diagnosis allowed her to have an even more special bond with her children.. The Michigan-based mom, 23, recently found out she has Mosaic Down syndrome, a condition ...

  7. This Mother Had A Baby At 50 Without Intervention. Here's ...

    www.aol.com/mother-had-baby-50-without-113000047...

    For women ages 40–44, the birth rate increased 4 percent between 2021 and 2022 (and has been continually inching up since 1985), while the birth rate for women ages 45 and over increased 12 percent.

  8. Chromosome abnormality - Wikipedia

    en.wikipedia.org/wiki/Chromosome_abnormality

    Chromosome anomalies can be inherited from a parent or be "de novo". This is why chromosome studies are often performed on parents when a child is found to have an anomaly. If the parents do not possess the abnormality it was not initially inherited; however, it may be transmitted to subsequent generations. [citation needed]

  9. Polysomy - Wikipedia

    en.wikipedia.org/wiki/Polysomy

    Trisomy 21 – Down syndrome, an example of a polysomy at chromosome 21. Polysomy is a condition found in many species, including fungi, plants, insects, and mammals, in which an organism has at least one more chromosome than normal, i.e., there may be three or more copies of the chromosome rather than the expected two copies. [1]