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RNA origami mechanism. RNA origami is the nanoscale folding of RNA, enabling the RNA to create particular shapes to organize these molecules. [1] It is a new method that was developed by researchers from Aarhus University and California Institute of Technology. [2] RNA origami is synthesized by enzymes that fold RNA into particular shapes.
The Nussinov algorithm is a nucleic acid structure prediction algorithm used in computational biology to predict the folding of an RNA molecule that makes use of dynamic programming principles. [1] The algorithm was developed by Ruth Nussinov in the late 1970s.
Ribosome profiling, or Ribo-Seq (also named ribosome footprinting), is an adaptation of a technique developed by Joan Steitz and Marilyn Kozak almost 50 years ago that Nicholas Ingolia and Jonathan Weissman adapted to work with next generation sequencing that uses specialized messenger RNA sequencing to determine which mRNAs are being actively translated.
Transfer RNA (tRNA) is a small RNA chain of about 80 nucleotides that transfers a specific amino acid to a growing polypeptide chain at the ribosomal site of protein synthesis during translation. It has sites for amino acid attachment and an anticodon region for codon recognition that binds to a specific sequence on the messenger RNA chain ...
The A-minor motif is among the most common RNA structural motifs in the ribosome, where it contributes to the binding of tRNA to the 23S subunit. [43] They most often stabilize RNA duplex interactions in loops and helices, such as in the core of group II introns. [6] An interesting example of A-minor is its role in anticodon recognition. The ...
Immigration advocacy groups and Democratic leaders are seeking to disrupt President-elect Donald Trump's plan to deport millions of undocumented immigrants by pre-drafting lawsuits that could be ...
Stem-loops occur in pre-microRNA structures and most famously in transfer RNA, which contain three true stem-loops and one stem that meet in a cloverleaf pattern.The anticodon that recognizes a codon during the translation process is located on one of the unpaired loops in the tRNA.
"One of the best features is the built-in timer that ensures I’m brushing for the dentist-recommended two minutes," wrote another enthusiastic shopper. "It even pauses every 30 seconds ...