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Mupirocin, sold under the brand name Bactroban among others, is a topical antibiotic useful against superficial skin infections such as impetigo or folliculitis. [ 5 ] [ 6 ] [ 7 ] It may also be used to get rid of methicillin-resistant S. aureus (MRSA) when present in the nose without symptoms. [ 6 ]
In addition, researchers have demonstrated that eradicating S. aureus from the anterior nares also utilizing intranasal mupirocin ointment reduced surgical site infection rates up to 58% in hospitalized patients who were nasal carriers. [77]
It is available in the U.S. as an over-the-counter drug for topical administration, with brand names including Domeboro (Moberg Pharma), Domeboro Otic (ear drops), Star-Otic, and Borofair. [1] The preparation has astringent and antibacterial properties and may be used to treat a number of skin conditions, including insect bites and stings ...
Kenacomb ear drops, containing triamcinolone acetonide, neomycin and gramicidin (antibiotics) and nystatin [21] Sofradex ear drops containing neomycin and gramicidin (antibiotics) plus dexamethasone (a steroid) [22] Antibiotics for ear infections are prescribed for infections that are recurrent or difficult for the body to clear.
Mupirocin 2% ointment can be effective at reducing the size of lesions. A secondary covering of clothing is preferred. [ 79 ] As shown in an animal study with diabetic mice, the topical application of a mixture of sugar (70%) and 3% povidone-iodine paste is an effective agent for the treatment of diabetic ulcers with MRSA infection.
Treatment is typically with antibiotic creams such as mupirocin or fusidic acid. [3] [5] Antibiotics by mouth, such as cefalexin, may be used if large areas are affected. [3] Antibiotic-resistant forms have been found. [3] Healing generally occurs without scarring. [7] Impetigo affected about 140 million people (2% of the world population) in ...
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The use of mupirocin ointment can reduce the rate of infections due to nasal carriage of S. aureus. [141] There is limited evidence that nasal decontamination of S. aureus using antibiotics or antiseptics can reduce the rates of surgical site infections.
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