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Small intestinal bacterial overgrowth (SIBO), also termed bacterial overgrowth, or small bowel bacterial overgrowth syndrome (SBBOS), is a disorder of excessive bacterial growth in the small intestine. Unlike the colon (or large bowel), which is rich with bacteria, the small bowel usually has fewer than 100,000 organisms per millilitre. [1]
Methanobrevibacter smithii is the predominant methanogenic archaeon in the microbiota of the human gut. [1] M. smithii has a coccobacillus shape.It plays an important role in the efficient digestion of polysaccharides (complex sugars) by consuming the end products of bacterial fermentation (H 2, CO 2, acetate, and formate). [2]
Methanogens can also be used as probiotics. [25] This is possible since methanogens are capable of using trimethylamine as a substrate for methanogenesis. [25] Trimethylamine is produced in the human intestines by intestinal bacteria. [25] An increase of trimethylamine may cause cardiovascular disease. [25]
The overgrowth of bacteria in the small intestine is prevented by various mechanical and chemical factors which include the constant peristaltic movement of contents along the length of the gastrointestinal tract and the antibacterial properties of gastric secretions, pancreatic secretions and bile. [citation needed]
Stomach pain or tummy troubles are among the most common ailments that affect children and adults alike. Feelings of bloating, cramping, constipation or nausea often occur because of something ...
Bacteria in the human gut’s intestines are the most diverse in the human body and play a vital role in human health. In the gastrointestinal tract, dysbiosis manifests particularly during small intestinal bacterial overgrowth (SIBO), commonly caused by a decrease in the passage of food and waste through the gastrointestinal tract following surgery or other pre-existing conditions. [17]
Treatment targets nutritional support, improving intestinal motility, and minimizing surgical intervention. [4] Bacterial overgrowth of the small intestine can occur in chronic cases – presenting as malabsorption, diarrhea, and nutrient deficiencies [12] – which may require the use of antibiotics.
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