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Ivermectin is an antiparasitic drug. [7] After its discovery in 1975, [8] its first uses were in veterinary medicine to prevent and treat heartworm and acariasis. [9] Approved for human use in 1987, [10] it is used to treat infestations including head lice, scabies, river blindness (onchocerciasis), strongyloidiasis, trichuriasis, ascariasis and lymphatic filariasis.
Ball-and-stick model of Ivermectin. Ivermectin is an antiparasitic drug that is well established for use in animals and people. [1] The World Health Organization (WHO), [2] the European Medicines Agency (EMA), [3] the United States Food and Drug Administration (FDA), [4] and the Infectious Diseases Society of America (IDSA) [5] all advise against using ivermectin in an attempt to treat or ...
Treatment of sheep is normally unnecessary, because they are not usually affected by the infection. [5] Ivermectin and benzimidazole can be used to kill the adult worms in goats. Daily doses of fenbendazole or albendazole for 1-2 weeks will destroy all life stages in goats.
Sheep and goats are both small ruminants with cosmopolitan distributions due to their being kept historically and in modern times as grazers both individually and in herds in return for their production of milk, wool, and meat. [1] As such, the diseases of these animals are of great economic importance to humans.
Mange (/ ˈ m eɪ n dʒ /) is a type of skin disease caused by parasitic mites. [1] Because various species of mites also infect plants, birds and reptiles, the term "mange", or colloquially "the mange", suggesting poor condition of the skin and fur due to the infection, is sometimes reserved for pathological mite-infestation of nonhuman mammals.
These mites remain external to the true outer layer of the skin (the epidermis) which also lines the tube of the hair follicle. However, the mites appear to be deep within the skin in the sense of being below the general outer surface of the host. The mites fit in the narrow space between the hair and the tube of the follicle.
Mebendazole (for most nematode infections) Pyrantel pamoate (for most nematode infections) Thiabendazole (for roundworm infections) Diethylcarbamazine (for treatment of Lymphatic filariasis) Ivermectin (for prevention of river blindness)
Paramphistomiasis is considered a neglected tropical disease, with no prescription drug for treatment and control. Thus management of infection is based mainly on control of the snail population. Drugs shown to be effective are resorantel, oxyclozanide, clorsulon, ivermectin, niclosamide, bithional and levamisole.
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