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Theophylline, also known as 1,3-dimethylxanthine, is a drug that inhibits phosphodiesterase and blocks adenosine receptors. [1] ... Adverse effects
The common side effects of Tedral include gastrointestinal disturbances, dizziness, headache and lightheadedness. [ 3 ] [ 4 ] [ 5 ] However, at high dose, it may lead to cardiac arrhythmias , hypertension , seizures or other serious cardiovascular and/or central nervous system adverse effects.
[9] [7] [10] A ratio of 5:1 theophylline to ephedrine is usually used in combinations of the drugs. [11] Later research found that the combination was no more effective for asthma than theophylline alone but produced more side effects. [9] [1] [12] [7]
Preventing Cardiovascular Disease. The development of cardiovascular disease is strongly associated with your lifestyle habits. You can minimize your chances of developing cardiovascular disease by:
A mouse study on the potentiating effects of methylxanthines coadministered with mitomycin C on teratogenicity reported the incidence of birth defects for caffeine, theophylline, and paraxanthine to be 94.2%, 80.0%, and 16.9%, respectively; additionally, average birth weight decreased significantly in mice exposed to caffeine or theophylline ...
The beneficial effects of small alkyl groups on the heterocycle could be to twist the central ring away from exact coplanarity with the heterocyclic ring. There is a similar twist in cAMP and there is general agreement that high affinity PDE3 inhibitors should adopt an energetically favoured planar conformation that mimics the anti conformation ...
History tells us that matters like marriage equality, voting rights, abortion access and campaign finance are often adjudicated through the court system.
The therapeutic range for the prevention of the pre-eclamptic uterine contractions is: 4.0–7.0 mEq/L. [10] As per Lu and Nightingale, [11] serum magnesium concentrations associated with maternal toxicity (also neonate depression, hypotonia and low Apgar scores) are: [citation needed] 7.0–10.0 mEq/L – Loss of patellar reflex
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