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Mosquito bite allergies are informally classified as 1) the skeeter syndrome, i.e., severe local skin reactions sometimes associated with low-grade fever; 2) systemic reactions that range from high-grade fever, lymphadenopathy, abdominal pain, and/or diarrhea to, very rarely, life-threatening symptoms of anaphylaxis; and 3) severe and often ...
Although less common than ICD, ACD is accepted to be the most prevalent form of immunotoxicity found in humans. [1] By its allergic nature, this form of contact dermatitis is a hypersensitive reaction that is atypical within the population. The mechanisms by which these reactions occur are complex, with many levels of fine control.
Purpura, arthritis, and abdominal pain are known as the "classic triad" of Henoch–Schönlein purpura. [5] Purpura occur in all cases, joint pains and arthritis in 80%, and abdominal pain in 62%. Some include gastrointestinal hemorrhage as a fourth criterion; this occurs in 33% of cases, sometimes, but not necessarily always, due to ...
The patch tests were based on the concept of a type IV hypersensitivity reaction where there is exposure of allergens to skin and checking for the development of contact dermatitis in that area. This test involves the application of suspected irritant to a part of the skin and cover it with impermeable material and attached to the skin with the ...
The symptoms of DRESS syndrome usually begin 2 to 6 weeks but uncommonly up to 8–16 weeks after exposure to an offending drug. Symptoms generally include fever, an often itchy rash which may be morbilliform or consist mainly of macules or plaques, facial edema (i.e. swelling, which is a hallmark of the disease), enlarged and sometimes painful lymph nodes, and other symptoms due to ...
In most cases skin lesions do not cause symptoms, however itching, burning, or pain may occur. [5] Frequently reported symptoms include mild fever, muscle pain, joint pain, or an overall feeling of discomfort. [6] [8] Additional symptoms depend on the cause of the vasculitis and if other organ systems are involved.
In-vitro studies indicate that human urine can trigger toxin release and increase pain caused by various jellyfish species. The most effective measure for treating a jellyfish sting is immersing the affected area in a hot bath with water temperature between 40 and 45 °C (104 and 113 °F) for approximately 20 minutes.
The oxidized porphyrins initiate degranulation of dermal mast cells, [19] which release proteases that catabolize the surrounding proteins. [20] This begins a cell-mediated positive feedback loop which matches the description of a type 4 delayed hypersensitivity reaction.