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Ewe with scrapie with weight loss and hunched appearance Same ewe as above with bare patches on rear end from scraping. Scrapie (/ ˈ s k r eɪ p i /) is a fatal, degenerative disease affecting the nervous systems of sheep and goats. [1] It is one of several transmissible spongiform encephalopathies (TSEs), and as such it is thought to be ...
5621 19122 Ensembl ENSG00000171867 ENSMUSG00000079037 UniProt P04156 P04925 RefSeq (mRNA) NM_183079 NM_000311 NM_001080121 NM_001080122 NM_001080123 NM_001271561 NM_001278256 NM_011170 RefSeq (protein) NP_000302 NP_001073590 NP_001073591 NP_001073592 NP_001258490 NP_898902 NP_000302.1 NP_001073590.1 NP_001073591.1 NP_001073592.1 NP_898902.1 NP_001265185 NP_035300 Location (UCSC) Chr 20: 4.69 ...
BSE is a degenerative infection of the central nervous system in cattle. It is a fatal disease, similar to scrapie in sheep and goats, caused by a prion.A major epizootic affected the UK, and to a lesser extent a number of other countries, between 1986 and the 2000s, infecting more than 190,000 animals, not counting those that remained undiagnosed.
In his 1998 PNAS review article on Prions, Prusiner wrote: [10] "The idea that scrapie prions were composed of an amyloidogenic protein was truly heretical when it was introduced" (by Tikvah Alper [11] [12]). Encephalopathy was a mysterious disease that attacks the brain, and leaves the brains of its victims full of holes.
Schematic images Healthy Yes Brain Machine Interface Platform Different types of data related to brain machine interface Human, Monkey Macroscopic, Neuron Images, Numerical Healthy No BrainMap.org fMRI coordinate database Human Macroscopic Descriptive Healthy Yes [10] BrainMaps: Atlas, high resolution stained sections from brains
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A 2006 study appears to refute the role of spiroplasmas in the best small animal scrapie model (hamsters). [3] Bastian et al. (2007) have responded to this challenge with the isolation of a spiroplasma species from scrapie-infected tissue, grown it in cell-free culture, and demonstrated its infectivity in ruminants. [4]