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Another alternative to oligoclonal bands for MS diagnosis is the MRZ-reaction (MRZR), a polyspecific antiviral immune response against the viruses of measles, rubella and zoster found in 1992. [ 22 ] In some reports the MRZR showed a lower sensitivity than OCB (70% vs. 100%), but a higher specificity (92% vs. 69%) for MS. [ 22 ]
Omsk hemorrhagic fever is caused by Omsk hemorrhagic fever virus (OHFV), a member of the Flavivirus family. The current species name is Orthoflavivirus omskense [4] according to International Committee on Taxonomy of Viruses taxonomy standards. The virus was discovered by Mikhail Chumakov and his colleagues between 1945 and 1947 in Omsk, Russia.
Multiple sclerosis diagnosis can only be made when there is proof of lesions disseminated in time and in space. Therefore, when damage in the CNS is big enough to be seen. It would be desirable to make it faster. The ideal diagnosis schema would be able to determine for any given subject, if he will develop MS, at any point in his life, and when.
In clinical practice, post-test probabilities are often just estimated or even guessed. This is usually acceptable in the finding of a pathognomonic sign or symptom, in which case it is almost certain that the target condition is present; or in the absence of finding a sine qua non sign or symptom, in which case it is almost certain that the target condition is absent.
Differential diagnosis Compression of the upper spinal cord , multiple sclerosis , transverse myelitis , Behçet's disease , osteogenesis imperfecta In neurology , Lhermitte phenomenon , also called the barber chair phenomenon , is an uncomfortable "electrical" sensation that runs down the back and into the limbs.
The US Food and Drug Administration issued a Premarket Submission and Labeling Recommendations for Drugs of Abuse Screening Tests.Its availability was announced in the Federal Register, Vol. 68, No. 231 on December 2, 2003 and is listed under "Notices."
Tzanck smear test is useful for rapid diagnosis of mastocytoma in children Sebaceous hyperplasia: Clusters of sebocytes Seborrheic keratosis: Hyperkeratosis and horny cysts 87.5% sensitive and 80.8% specific Melanocytic nevi: Dermal and epidermal type nevoid cells 87.5% sensitive and 100% specific Eruptive vellus hair cysts: Abundant vellus hairs
A hypothetical ideal "gold standard" test has a sensitivity of 100% concerning the presence of the disease (it identifies all individuals with a well-defined disease process; it does not have any false-negative results) and a specificity of 100% (it does not falsely identify someone with a condition that does not have the condition; it does not have any false-positive results).