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A fundamental philosophy of medical oncology, including combination chemotherapy, is that different drugs work through different mechanisms, and that the results of using multiple drugs will be synergistic to some extent. Because they have different dose-limiting adverse effects, they can be given together at full doses in chemotherapy regimens ...
Cyclophosphamide (CP), also known as cytophosphane among other names, [3] is a medication used as chemotherapy and to suppress the immune system. [4] As chemotherapy it is used to treat lymphoma, multiple myeloma, leukemia, ovarian cancer, breast cancer, small cell lung cancer, neuroblastoma, and sarcoma. [4]
Multiple myeloma is the second-most prevalent blood cancer (10%) after non-Hodgkin's lymphoma. [154] It represents about 1.8% of all new cancers and 2.1% of all cancer deaths. [7] Multiple myeloma affects slightly more men than women.
Pages in category "Chemotherapy regimens used in multiple myeloma" The following 2 pages are in this category, out of 2 total. This list may not reflect recent changes .
The combination is then referred to as COP (cyclophosphamide, Oncovin, and prednisone or prednisolone) or CVP (cyclophosphamide, vincristine, and prednisone or prednisolone). As elderly patients have a greater risk of toxicity from the drugs, an option is to use an attenuated drug regimen, called miniCHOP.
As of 2021, U.S. News & World Report ranks Mayo Clinic Alix School of Medicine #11 (tie) on their "Best Medical Schools: Research" list. [7] MCASOM is the most selective medical school in the United States, with the lowest acceptance rate (2.1%) among schools submitting data for the 2017-2018 application cycle.
In pharmacokinetics, a loading dose is an initial higher dose of a drug that may be given at the beginning of a course of treatment before dropping down to a lower maintenance dose. [ 1 ] A loading dose is most useful for drugs that are eliminated from the body relatively slowly, i.e. have a long systemic half-life .
The Mayo Clinic School of Health Sciences (MCSHS; formerly known as Mayo School of Health Sciences [1]) is an accredited, private, nonprofit school of higher education specializing in allied health education. MCSHS operates within the Mayo Clinic College of Medicine and Science, which is the educational division of Mayo Clinic. As such, MCSHS ...