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The age term is (140 – age). This means that a 20-year-old person (140 – 20 = 120) will have twice the creatinine clearance as an 80-year-old (140 – 80 = 60) for the same level of serum creatinine. The C-G equation assumes that a woman will have a 15% lower creatinine clearance than a man at the same level of serum creatinine.
Para-aminohippurate (PAH) clearance is a method used in renal physiology to measure renal plasma flow, which is a measure of renal function. [citation needed]PAH is completely removed from blood that passes through the kidneys (PAH undergoes both glomerular filtration and tubular secretion), and therefore the rate at which the kidneys can clear PAH from the blood reflects total renal plasma flow.
The urea reduction ratio (URR) is a dimensionless number used to quantify dialysis treatment adequacy. Definition = % Where: U ...
It is a more expensive test than serum creatinine (around $2 or $3, compared to $0.02 to $0.15), which can be measured with a Jaffe reaction. [82] [83] [84] Reference values differ in many populations and with sex and age. Across different studies, the mean reference interval (as defined by the 5th and 95th percentile) was between 0.52 and 0.98 ...
For example, a hazard ratio of 2 is thought to mean that a group has twice the chance of dying than a comparison group. In the Cox-model, this can be shown to translate to the following relationship between group survival functions : S 1 ( t ) = S 0 ( t ) r {\displaystyle S_{1}(t)=S_{0}(t)^{r}} (where r is the hazard ratio). [ 8 ]
Normalizing the RMSD facilitates the comparison between datasets or models with different scales. Though there is no consistent means of normalization in the literature, common choices are the mean or the range (defined as the maximum value minus the minimum value) of the measured data: [4]
Normal mean renal artery RI for an adult is 0.6 with 0.7 the upper limit of normal. In children, RI commonly exceeds 0.7 through 12 months of age and can remain above 0.7 through 4 years of age. [ 4 ]
where δ i is the distance between atom i and either a reference structure or the mean position of the N equivalent atoms. This is often calculated for the backbone heavy atoms C, N, O, and C α or sometimes just the C α atoms. Normally a rigid superposition which minimizes the RMSD is performed, and this minimum is returned.