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The epithelial sodium channel (ENaC), (also known as amiloride-sensitive sodium channel) is a membrane-bound ion channel that is selectively permeable to sodium ions (Na +).It is assembled as a heterotrimer composed of three homologous subunits α or δ, β, and γ, [2] These subunits are encoded by four genes: SCNN1A, SCNN1B, SCNN1G, and SCNN1D.
École nationale de l'aviation civile (ENAC) (National School of Civil Aviation) is one of 205 colleges (as of September 2018) accredited to award engineering degrees in France. ENAC is designated as a grande école by the Conférence des Grandes écoles (CGE), a non-profit organisation which certifies and monitors grandes écoles (including ...
The Ente Nazionale per l'Aviazione Civile (ENAC), English: Italian Civil Aviation Authority, [1] is the civil aviation authority of Italy. Its headquarters are located in Rome. [2] Legislative Decree no.250/97 established the existence of ENAC on 25 July 1997. [3] It is the equivalency of the United States Federal Aviation Administration.
The human gene SCNN1A is located in the short arm of chromosome 12 (12p3). [10] [11] Human SCNN1A includes 13 exons spanning about 29,000 bp. The protein coding region is located in exons 2-13. [11] The positions of introns are conserved in all four human ENaC genes. [12]
6338 20277 Ensembl ENSG00000168447 ENSMUSG00000030873 UniProt P51168 Q9WU38 RefSeq (mRNA) NM_000336 NM_001272023 NM_011325 RefSeq (protein) NP_000327 NP_001258952 NP_035455 Location (UCSC) Chr 16: 23.28 – 23.38 Mb Chr 7: 121.46 – 121.52 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse The SCNN1B gene encodes for the β subunit of the epithelial sodium channel ENaC in vertebrates ...
20278 Ensembl ENSG00000166828 ENSMUSG00000000216 UniProt P51170 Q9WU39 RefSeq (mRNA) NM_001039 NM_011326 RefSeq (protein) NP_001030 NP_035456 Location (UCSC) Chr 16: 23.18 – 23.22 Mb Chr 7: 121.33 – 121.37 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse The SCNN1G gene encodes for the γ subunit of the epithelial sodium channel ENaC in vertebrates. ENaC is assembled as a ...
This complex enhances transcription of specific DNA segments in the nucleus, leading to the formation of two protein transporters, Na+/K+ ATPase pump at the basolateral membrane and Na+ channel called ENaC, located at the apical membrane of the renal tubule cell. [6]
n/a Ensembl ENSG00000162572 n/a UniProt P51172 n/a RefSeq (mRNA) NM_001130413 NM_002978 n/a RefSeq (protein) NP_001123885 n/a Location (UCSC) Chr 1: 1.28 – 1.29 Mb n/a PubMed search n/a Wikidata View/Edit Human The SCNN1D gene encodes for the δ (delta) subunit of the epithelial sodium channel ENaC in vertebrates. ENaC is assembled as a heterotrimer composed of three homologous subunits α ...