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The seventh and eighth digits distinguish mutations outside the coding region. Letters such as L, N, Q, or S may follow an allele's designation to specify an expression level or other non-genomic data known about it. Thus, a completely described allele may be up to 9 digits long, not including the HLA-prefix and locus notation. [19
The locus coeruleus (/ s ɪ ˈ r uː l i ə s /) (LC), also spelled locus caeruleus or locus ceruleus, [1] is a nucleus in the pons of the brainstem involved with physiological responses to stress and panic. [2] It is a part of the reticular activating system in the reticular formation. [3]
Assertive community treatment (ACT) is an intensive and highly integrated approach for community mental health service delivery. [1] ACT teams serve individuals who have been diagnosed with serious and persistent forms of mental illness, predominantly but not exclusively the schizophrenia spectrum disorders.
A locus control region (LCR) is a long-range cis-regulatory element that enhances expression of linked genes at distal chromatin sites. It functions in a copy number-dependent manner and is tissue-specific, as seen in the selective expression of β-globin genes in erythroid cells . [ 1 ]
Emergency Severity Index (ESI): A Triage Tool for Emergency Department Care, Version 4. Implementation Handbook 2012 Edition. AHRQ. ISBN 978-1-58763-416-1. Gilboy N, Tanabe T, Travers D, Rosenau AM (2020). Emergency Severity Index (ESI): A Triage Tool for Emergency Department Care, Version 4. 2020 Edition (PDF). Emergency Nurses Association.
Once set, light chain class remains fixed for the life of the B lymphocyte. In a healthy individual, the total kappa-to-lambda ratio is roughly 2:1 in serum (measuring intact whole antibodies) or 1:1.5 if measuring free light chains, with a highly divergent ratio indicative of neoplasm. The free light chain ratio ranges from 0.26 to 1.65. [1]
Nursing care levels are different levels of care by which nursing services are provided for a patient. [ 1 ] [ 2 ] In the UK, they include "Bay Nursing", "Arm's Length Nursing" and "1:1 Nursing". The latter is also called "Specialling Nursing".
Multilocus sequence typing (MLST) is a technique in molecular biology for the typing of multiple loci, using DNA sequences of internal fragments of multiple housekeeping genes to characterize isolates of microbial species.